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| 23.04.2023 | 15:00 | ACD Nardò | - | Brindisi | 0:2 | |
| 15:00 | US Bitonto | - | FBC Gravina | 0:2 | ||
| 15:00 | Cavese | - | Martina | 1:2 | ||
| 15:00 | Città di Fasano | - | Afragolese | 0:1 | ||
| 15:00 | FC Francavilla | - | Lavello | 2:0 | ||
| 15:00 | Gladiator | - | Casarano | 0:0 | ||
| 15:00 | Matera Calcio | - | SS Barletta Calcio | 1:1 | ||
| 15:00 | Sporting Fulgor Molfetta | - | ASG Nocerina | 1:0 | ||
| 15:00 | Puteolana Internapoli | - | Team Altamura | 0:3 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Cavese | 32 | 19 | 9 | 4 | 60:33 | 27 | 66 |
| 2 |
|
Brindisi | 32 | 18 | 9 | 5 | 56:27 | 29 | 63 |
| 3 |
|
ACD Nardò | 32 | 17 | 11 | 4 | 44:21 | 23 | 62 |
| 4 |
|
SS Barletta Calcio | 32 | 15 | 13 | 4 | 36:26 | 10 | 58 |
| 5 |
|
Team Altamura | 32 | 14 | 11 | 7 | 47:31 | 16 | 53 |
| 6 |
|
Casarano | 32 | 12 | 17 | 3 | 43:30 | 13 | 53 |
| 7 |
|
Matera Calcio | 32 | 12 | 10 | 10 | 50:44 | 6 | 46 |
| 8 |
|
Città di Fasano | 32 | 11 | 10 | 11 | 41:39 | 2 | 43 |
| 9 |
|
Martina | 32 | 11 | 10 | 11 | 37:40 | -3 | 43 |
| 10 |
|
US Bitonto | 32 | 11 | 9 | 12 | 42:46 | -4 | 42 |
| 11 |
|
Gladiator | 32 | 8 | 12 | 12 | 40:51 | -11 | 36 |
| 12 |
|
Afragolese | 32 | 7 | 14 | 11 | 37:43 | -6 | 35 |
| 13 |
|
ASG Nocerina | 32 | 8 | 9 | 15 | 36:44 | -8 | 33 |
| 14 |
|
Sporting Fulgor Molfetta | 32 | 7 | 11 | 14 | 39:46 | -7 | 32 |
| 15 |
|
FBC Gravina | 32 | 6 | 14 | 12 | 26:40 | -14 | 32 |
| 16 |
|
FC Francavilla | 32 | 7 | 8 | 17 | 35:47 | -12 | 29 |
| 17 |
|
Lavello | 32 | 6 | 5 | 21 | 26:62 | -36 | 23 |
| 18 |
|
Puteolana Internapoli | 32 | 3 | 10 | 19 | 28:53 | -25 | 19 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
