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| 04.06.2022 | 13:00 | SFC Stern 1900 | - | Hansa Rostock II | 0:3 (0:1) | |
| 14:00 | Hertha Zehlendorf | - | Brandenburger SC Süd | 2:0 (1:0) | ||
| 14:00 | Ludwigsfelder FC | - | TSG Neustrelitz | 0:1 (0:0) | ||
| 14:00 | Eintracht Mahlsdorf | - | Rostocker FC | 3:0 (0:0) | ||
| 14:00 | MSV 1919 Neuruppin | - | 1. FC Lok Stendal | 4:1 (2:1) | ||
| 14:00 | MSV Pampow | - | Blau-Weiß 90 Berlin | 3:3 (1:1) | ||
| 14:00 | SC Staaken | - | CFC Hertha 06 | 3:2 (1:1) | ||
| 14:00 | Victoria Seelow | - | Greifswalder FC | 1:5 (1:2) | ||
| 14:00 | Torgelower FC Greif | - | FC Mecklenburg Schwerin | 3:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | ∅ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Greifswalder FC | 29 | 20 | 5 | 4 | 57:27 | 30 | 65 | 2.24 |
| 2 |
|
Hertha Zehlendorf | 30 | 21 | 3 | 6 | 64:25 | 39 | 66 | 2.20 |
| 3 |
|
Blau-Weiß 90 Berlin | 29 | 18 | 3 | 8 | 62:39 | 23 | 57 | 1.97 |
| 4 |
|
TSG Neustrelitz | 29 | 16 | 7 | 6 | 42:24 | 18 | 55 | 1.90 |
| 5 |
|
CFC Hertha 06 | 30 | 17 | 6 | 7 | 52:35 | 17 | 57 | 1.90 |
| 6 |
|
Rostocker FC | 29 | 17 | 2 | 10 | 66:28 | 38 | 53 | 1.83 |
| 7 |
|
SC Staaken | 30 | 15 | 8 | 7 | 57:34 | 23 | 53 | 1.77 |
| 8 |
|
Torgelower FC Greif | 29 | 14 | 6 | 9 | 59:32 | 27 | 48 | 1.66 |
| 9 |
|
Eintracht Mahlsdorf | 29 | 14 | 6 | 9 | 49:33 | 16 | 48 | 1.66 |
| 10 |
|
RSV Eintracht 1949 | 29 | 10 | 12 | 7 | 44:37 | 7 | 42 | 1.45 |
| 11 |
|
Hansa Rostock II | 29 | 11 | 8 | 10 | 63:48 | 15 | 41 | 1.41 |
| 12 |
|
MSV Pampow | 29 | 9 | 8 | 12 | 45:55 | -10 | 35 | 1.21 |
| 13 |
|
FC Mecklenburg Schwerin | 30 | 10 | 4 | 16 | 38:58 | -20 | 34 | 1.13 |
| 14 |
|
Ludwigsfelder FC | 30 | 9 | 6 | 15 | 31:45 | -14 | 33 | 1.10 |
| 15 |
|
MSV 1919 Neuruppin | 29 | 6 | 9 | 14 | 35:61 | -26 | 27 | 0.93 |
| 16 |
|
Brandenburger SC Süd | 30 | 4 | 7 | 19 | 22:50 | -28 | 19 | 0.63 |
| 17 |
|
SFC Stern 1900 | 29 | 3 | 8 | 18 | 28:63 | -35 | 17 | 0.59 |
| 18 |
|
Victoria Seelow | 30 | 4 | 4 | 22 | 31:84 | -53 | 16 | 0.53 |
| 19 |
|
1. FC Lok Stendal | 29 | 3 | 4 | 22 | 26:93 | -67 | 13 | 0.45 |
| Aufstieg | |
| Relegation | |
| Abstieg |
|
# Der Torgelower FC Greif zog sich nach Saisonende aus der Oberliga zurück. |
