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| 26.10.2018 | 23:00 | Cruz Azul Hidalgo | - | Pioneros de Cancún | 3:2 (1:1) | |
| 27.10.2018 | 03:00 | Murciélagos FC | - | Tecos Fútbol Club | 2:1 (0:1) | |
| 18:00 | Cimarrones de Sonora II | - | Atlético Reynosa | 0:2 (0:1) | ||
| 19:00 | Monarcas Morelia II | - | Loros UCOL | 2:1 (2:1) | ||
| 23:00 | Real Zamora | - | Albinegros Orizaba | 0:0 (0:0) | ||
| 23:00 | Sporting Canamy | - | Pumas UNAM II | 4:3 (4:3) | ||
| 23:00 | Tuzos de la UAZ | - | CF América II | 3:1 (1:1) | ||
| 28.10.2018 | 00:00 | Correcaminos UAT II | - | Pacific F. C. | 2:0 (0:0) | |
| 00:00 | Gavilanes de Matamoros | - | Alacranes de Durango | 0:0 (0:0) | ||
| 00:00 | Yalmakan FC | - | Coyotes de Tlaxcala | 1:1 (0:1) | ||
| 00:00 | Cocodrilos de Tabasco | - | Deportivo Toluca II | 1:0 (1:0) | ||
| 00:00 | Tepatitlán | - | Coras de Nayarit | 3:2 (1:1) | ||
| 18:00 | Club Necaxa II | - | Deportivo Guadalajara II | 1:1 (0:0) | ||
| 19:00 | Leones Negros II | - | Dorados UACH | 2:1 (1:1) | ||
| 22:30 | Reboceros de La Piedad | - | Tuxtla FC | 0:3 (0:2) | ||
| 30.10.2018 | 00:00 | Club Irapuato | - | Inter Playa | 3:0 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 10 | 9 | 0 | 1 | 22:7 | 15 | 31 |
| 2 |
|
Deportivo Guadalajara II | 10 | 6 | 3 | 1 | 17:7 | 10 | 25 |
| 3 |
|
Murciélagos FC | 10 | 6 | 2 | 2 | 17:10 | 7 | 23 |
| 4 |
|
Gavilanes de Matamoros | 10 | 6 | 2 | 2 | 16:9 | 7 | 22 |
| 5 |
|
Tepatitlán | 10 | 6 | 2 | 2 | 17:12 | 5 | 22 |
| 6 |
|
Tuxtla FC | 10 | 6 | 1 | 3 | 20:10 | 10 | 21 |
| 7 |
|
Tuzos de la UAZ | 10 | 5 | 4 | 1 | 17:12 | 5 | 21 |
| 8 |
|
Cruz Azul Hidalgo | 10 | 5 | 2 | 3 | 16:12 | 4 | 21 |
| 9 |
|
Loros UCOL | 10 | 4 | 2 | 4 | 19:11 | 8 | 20 |
| 10 |
|
Club Necaxa II | 10 | 4 | 5 | 1 | 10:8 | 2 | 20 |
| 11 |
|
Deportivo Toluca II | 10 | 4 | 5 | 1 | 19:14 | 5 | 19 |
| 12 |
|
Correcaminos UAT II | 10 | 4 | 4 | 2 | 14:9 | 5 | 19 |
| 13 |
|
Inter Playa | 10 | 5 | 1 | 4 | 15:14 | 1 | 18 |
| 14 |
|
Coras de Nayarit | 10 | 4 | 3 | 3 | 14:13 | 1 | 17 |
| 15 |
|
Monarcas Morelia II | 10 | 4 | 3 | 3 | 19:8 | 11 | 16 |
| 16 |
|
Dorados UACH | 10 | 3 | 3 | 4 | 10:14 | -4 | 16 |
| 17 |
|
Pumas UNAM II | 10 | 4 | 0 | 6 | 15:15 | 0 | 15 |
| 18 |
|
Coyotes de Tlaxcala | 10 | 3 | 4 | 3 | 11:11 | 0 | 15 |
| 19 |
|
Albinegros Orizaba | 10 | 3 | 4 | 3 | 5:6 | -1 | 14 |
| 20 |
|
Leones Negros II | 10 | 3 | 3 | 4 | 17:17 | 0 | 13 |
| 21 |
|
Atlético Reynosa | 10 | 2 | 3 | 5 | 10:10 | 0 | 13 |
| 22 |
|
Reboceros de La Piedad | 10 | 2 | 3 | 5 | 10:17 | -7 | 13 |
| 23 |
|
Tecos Fútbol Club | 10 | 2 | 2 | 6 | 9:16 | -7 | 13 |
| 24 |
|
Yalmakan FC | 10 | 2 | 4 | 4 | 9:10 | -1 | 12 |
| 25 |
|
Cocodrilos de Tabasco | 10 | 2 | 3 | 5 | 11:14 | -3 | 12 |
| 26 |
|
CF América II | 10 | 2 | 4 | 4 | 13:19 | -6 | 12 |
| 27 |
|
Real Zamora | 10 | 3 | 1 | 6 | 11:17 | -6 | 12 |
| 28 |
|
Sporting Canamy | 10 | 3 | 2 | 5 | 14:23 | -9 | 12 |
| 29 |
|
Pacific F. C. | 10 | 2 | 3 | 5 | 11:23 | -12 | 11 |
| 30 |
|
Pioneros de Cancún | 10 | 1 | 4 | 5 | 12:19 | -7 | 9 |
| 31 |
|
Alacranes de Durango | 10 | 1 | 4 | 5 | 6:16 | -10 | 8 |
| 32 |
|
Cimarrones de Sonora II | 10 | 0 | 2 | 8 | 5:28 | -23 | 2 |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Abstieg |
