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| 06.06.2021 | 16:00 | Afragolese | - | ASG Nocerina | 1:0 | |
| 16:00 | Giugliano | - | Gladiator | 0:2 | ||
| 16:00 | Cassino Calcio 1924 | - | ASD SS Nola 1925 | 2:3 | ||
| 16:00 | Lanusei Calcio | - | Arzachena | 2:0 | ||
| 16:00 | Sassari Latte Dolce | - | Team Nuova Florida | 2:2 | ||
| 16:00 | Muravera | - | Formia | 1:2 | ||
| 16:00 | AC Savoia 1908 | - | SEF Torres 1903 | 1:1 | ||
| 16:00 | Latina Calcio | - | ASD Carbonia Calcio | 3:1 | ||
| 16:00 | ASD Vis Artena | - | Monterosi FC | 1:3 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Monterosi FC | 32 | 23 | 8 | 1 | 56:20 | 36 | 77 |
| 2 |
|
Latina Calcio | 32 | 18 | 8 | 6 | 57:23 | 34 | 62 |
| 3 |
|
ASD Vis Artena | 32 | 16 | 4 | 12 | 51:41 | 10 | 52 |
| 4 |
|
AC Savoia 1908 | 32 | 12 | 15 | 5 | 36:21 | 15 | 51 |
| 5 |
|
ASG Nocerina | 32 | 12 | 13 | 7 | 47:32 | 15 | 49 |
| 6 |
|
Formia | 32 | 12 | 11 | 9 | 48:35 | 13 | 47 |
| 7 |
|
Muravera | 32 | 13 | 7 | 12 | 42:39 | 3 | 46 |
| 8 |
|
Lanusei Calcio | 32 | 11 | 11 | 10 | 41:34 | 7 | 44 |
| 9 |
|
ASD Carbonia Calcio | 32 | 11 | 9 | 12 | 51:52 | -1 | 42 |
| 10 |
|
Sassari Latte Dolce | 32 | 10 | 10 | 12 | 39:37 | 2 | 40 |
| 11 |
|
Cassino Calcio 1924 | 32 | 9 | 13 | 10 | 39:43 | -4 | 40 |
| 12 |
|
Team Nuova Florida | 32 | 8 | 14 | 10 | 36:44 | -8 | 38 |
| 13 |
|
Gladiator | 32 | 8 | 12 | 12 | 33:43 | -10 | 36 |
| 14 |
|
Arzachena | 32 | 7 | 14 | 11 | 38:47 | -9 | 35 |
| 15 |
|
SEF Torres 1903 | 32 | 7 | 10 | 15 | 28:45 | -17 | 31 |
| 16 |
|
Afragolese | 32 | 8 | 7 | 17 | 36:57 | -21 | 31 |
| 17 |
|
ASD SS Nola 1925 | 32 | 6 | 13 | 13 | 33:55 | -22 | 30 |
| 18 |
|
Giugliano | 32 | 5 | 5 | 22 | 22:65 | -43 | 20 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
