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| 06.01.2021 | 12:30 | Cagliari Calcio | - | Benevento Calcio | 1:2 (1:2) | |
| 15:00 | Atalanta | - | Parma Calcio 1913 | 3:0 (1:0) | ||
| 15:00 | Bologna FC | - | Udinese Calcio | 2:2 (2:1) | ||
| 15:00 | FC Crotone | - | AS Roma | 1:3 (0:3) | ||
| 15:00 | Lazio Roma | - | ACF Fiorentina | 2:1 (1:0) | ||
| 15:00 | Sampdoria | - | Inter | 2:1 (2:0) | ||
| 15:00 | Sassuolo Calcio | - | Genoa CFC | 2:1 (0:0) | ||
| 15:00 | Torino FC | - | Hellas Verona | 1:1 (0:0) | ||
| 18:00 | SSC Napoli | - | Spezia Calcio | 1:2 (0:0) | ||
| 20:45 | AC Milan | - | Juventus | 1:3 (1:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
AC Milan | 16 | 11 | 4 | 1 | 35:19 | 16 | 37 |
| 2 |
|
Inter | 16 | 11 | 3 | 2 | 41:21 | 20 | 36 |
| 3 |
|
Juventus | 16 | 9 | 6 | 1 | 34:16 | 18 | 33 |
| 4 |
|
AS Roma | 16 | 10 | 3 | 3 | 35:24 | 11 | 33 |
| 5 |
|
Atalanta | 16 | 8 | 5 | 3 | 37:22 | 15 | 29 |
| 6 |
|
Sassuolo Calcio | 16 | 8 | 5 | 3 | 29:23 | 6 | 29 |
| 7 |
|
SSC Napoli | 16 | 9 | 1 | 6 | 33:17 | 16 | 28 |
| 8 |
|
Lazio Roma | 16 | 7 | 4 | 5 | 25:25 | 0 | 25 |
| 9 |
|
Hellas Verona | 16 | 6 | 6 | 4 | 20:15 | 5 | 24 |
| 10 |
|
Benevento Calcio | 16 | 6 | 3 | 7 | 19:26 | -7 | 21 |
| 11 |
|
Sampdoria | 16 | 6 | 2 | 8 | 25:26 | -1 | 20 |
| 12 |
|
Bologna FC | 16 | 4 | 5 | 7 | 23:29 | -6 | 17 |
| 13 |
|
Udinese Calcio | 16 | 4 | 5 | 7 | 18:24 | -6 | 17 |
| 14 |
|
ACF Fiorentina | 16 | 3 | 6 | 7 | 17:23 | -6 | 15 |
| 15 |
|
Cagliari Calcio | 16 | 3 | 5 | 8 | 23:33 | -10 | 14 |
| 16 |
|
Spezia Calcio | 16 | 3 | 5 | 8 | 21:31 | -10 | 14 |
| 17 |
|
Torino FC | 16 | 2 | 6 | 8 | 26:33 | -7 | 12 |
| 18 |
|
Parma Calcio 1913 | 16 | 2 | 6 | 8 | 13:31 | -18 | 12 |
| 19 |
|
Genoa CFC | 16 | 2 | 5 | 9 | 16:30 | -14 | 11 |
| 20 |
|
FC Crotone | 16 | 2 | 3 | 11 | 16:38 | -22 | 9 |
| Champions League | |
| Europa League | |
| Europa Conference League Quali. | |
| Abstieg |
