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| 01.05.2021 | 19:30 | Beşiktaş | - | Hatayspor | 7:0 (5:0) | |
| 02.05.2021 | 15:00 | Antalyaspor | - | Göztepe | 2:3 (1:1) | |
| 15:00 | Denizlispor | - | Çaykur Rizespor | 0:1 (0:0) | ||
| 15:00 | Konyaspor | - | Fatih Karagümrük SK | 5:1 (1:1) | ||
| 19:30 | Gençlerbirliği | - | Galatasaray | 0:2 (0:1) | ||
| 03.05.2021 | 15:00 | İstanbul Başakşehir | - | MKE Ankaragücü | 2:1 (0:1) | |
| 15:00 | Kasımpaşa SK | - | Alanyaspor | 3:0 (2:0) | ||
| 15:00 | Yeni Malatyaspor | - | Kayserispor | 1:1 (0:1) | ||
| 19:30 | Fenerbahçe | - | BB Erzurumspor | 3:1 (3:0) | ||
| 19:30 | Gaziantep FK | - | Sivasspor | 0:1 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Beşiktaş | 37 | 25 | 6 | 6 | 85:38 | 47 | 81 |
| 2 |
|
Fenerbahçe | 37 | 23 | 7 | 7 | 67:37 | 30 | 76 |
| 3 |
|
Galatasaray | 37 | 23 | 6 | 8 | 70:33 | 37 | 75 |
| 4 |
|
Trabzonspor | 37 | 17 | 13 | 7 | 45:34 | 11 | 64 |
| 5 |
|
Sivasspor | 37 | 14 | 16 | 7 | 50:41 | 9 | 58 |
| 6 |
|
Alanyaspor | 38 | 16 | 9 | 13 | 55:42 | 13 | 57 |
| 7 |
|
Hatayspor | 37 | 16 | 9 | 12 | 60:51 | 9 | 57 |
| 8 |
|
Gaziantep FK | 37 | 14 | 12 | 11 | 54:46 | 8 | 54 |
| 9 |
|
Göztepe | 37 | 13 | 12 | 12 | 55:51 | 4 | 51 |
| 10 |
|
Fatih Karagümrük SK | 37 | 13 | 12 | 12 | 52:49 | 3 | 51 |
| 11 |
|
Konyaspor | 37 | 11 | 12 | 14 | 47:47 | 0 | 45 |
| 12 |
|
Çaykur Rizespor | 37 | 11 | 12 | 14 | 48:59 | -11 | 45 |
| 13 |
|
Antalyaspor | 38 | 9 | 16 | 13 | 40:53 | -13 | 43 |
| 14 |
|
İstanbul Başakşehir | 37 | 11 | 10 | 16 | 41:55 | -14 | 43 |
| 15 |
|
Yeni Malatyaspor | 37 | 9 | 14 | 14 | 43:49 | -6 | 41 |
| 16 |
|
Kasımpaşa SK | 37 | 10 | 10 | 17 | 42:54 | -12 | 40 |
| 17 |
|
Kayserispor | 37 | 9 | 12 | 16 | 34:50 | -16 | 39 |
| 18 |
|
MKE Ankaragücü | 37 | 10 | 8 | 19 | 44:59 | -15 | 38 |
| 19 |
|
BB Erzurumspor | 38 | 9 | 10 | 19 | 41:65 | -24 | 37 |
| 20 |
|
Gençlerbirliği | 37 | 9 | 8 | 20 | 37:66 | -29 | 35 |
| 21 |
|
Denizlispor | 37 | 6 | 10 | 21 | 36:67 | -31 | 28 |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Abstieg |
