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| 23.04.2021 | 19:30 | Gençlerbirliği | - | Çaykur Rizespor | 2:1 (1:0) | |
| 24.04.2021 | 12:30 | Konyaspor | - | Hatayspor | 0:0 (0:0) | |
| 15:00 | Trabzonspor | - | Fatih Karagümrük SK | 2:0 (1:0) | ||
| 19:30 | Antalyaspor | - | Galatasaray | 0:1 (0:0) | ||
| 19:30 | Beşiktaş | - | Kayserispor | 3:1 (2:1) | ||
| 19:30 | Denizlispor | - | Sivasspor | 1:1 (0:1) | ||
| 25.04.2021 | 12:30 | Yeni Malatyaspor | - | MKE Ankaragücü | 2:1 (0:0) | |
| 15:00 | Gaziantep FK | - | BB Erzurumspor | 2:3 (0:0) | ||
| 15:00 | İstanbul Başakşehir | - | Alanyaspor | 0:0 (0:0) | ||
| 19:30 | Fenerbahçe | - | Kasımpaşa SK | 3:2 (3:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Beşiktaş | 35 | 23 | 6 | 6 | 75:36 | 39 | 75 |
| 2 |
|
Fenerbahçe | 35 | 22 | 6 | 7 | 64:36 | 28 | 72 |
| 3 |
|
Galatasaray | 35 | 21 | 6 | 8 | 67:33 | 34 | 69 |
| 4 |
|
Trabzonspor | 36 | 17 | 12 | 7 | 44:33 | 11 | 63 |
| 5 |
|
Alanyaspor | 36 | 16 | 8 | 12 | 55:39 | 16 | 56 |
| 6 |
|
Hatayspor | 35 | 15 | 9 | 11 | 57:43 | 14 | 54 |
| 7 |
|
Sivasspor | 35 | 12 | 16 | 7 | 48:41 | 7 | 52 |
| 8 |
|
Gaziantep FK | 35 | 13 | 12 | 10 | 53:45 | 8 | 51 |
| 9 |
|
Fatih Karagümrük SK | 35 | 13 | 11 | 11 | 49:42 | 7 | 50 |
| 10 |
|
Göztepe | 35 | 12 | 11 | 12 | 51:48 | 3 | 47 |
| 11 |
|
Konyaspor | 35 | 10 | 12 | 13 | 42:45 | -3 | 42 |
| 12 |
|
Çaykur Rizespor | 35 | 10 | 12 | 13 | 45:56 | -11 | 42 |
| 13 |
|
Antalyaspor | 36 | 9 | 15 | 12 | 36:48 | -12 | 42 |
| 14 |
|
Yeni Malatyaspor | 35 | 9 | 13 | 13 | 42:47 | -5 | 40 |
| 15 |
|
MKE Ankaragücü | 35 | 10 | 8 | 17 | 43:56 | -13 | 38 |
| 16 |
|
Kasımpaşa SK | 36 | 9 | 10 | 17 | 39:54 | -15 | 37 |
| 17 |
|
İstanbul Başakşehir | 35 | 9 | 10 | 16 | 37:53 | -16 | 37 |
| 18 |
|
BB Erzurumspor | 36 | 9 | 10 | 17 | 39:60 | -21 | 37 |
| 19 |
|
Kayserispor | 35 | 8 | 11 | 16 | 27:46 | -19 | 35 |
| 20 |
|
Gençlerbirliği | 35 | 9 | 8 | 18 | 36:61 | -25 | 35 |
| 21 |
|
Denizlispor | 35 | 6 | 10 | 19 | 33:60 | -27 | 28 |
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| Europa Conference League Quali. | |
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