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| 12.11.2022 | 10:00 | Slavia Praha | - | FK Dukla Praha | 0:1 (0:1) | |
| 10:30 | Viktoria Plzeň | - | FK Viagem Příbram | 7:1 (4:1) | ||
| 11:00 | Dynamo České Budějovice | - | FK Pardubice | 1:3 (1:3) | ||
| 11:00 | Sigma Olomouc | - | Vysočina Jihlava | 2:3 (0:1) | ||
| 11:00 | FC Zbrojovka Brno | - | MFK Karviná | 1:1 (1:0) | ||
| 11:30 | 1. FC Slovácko | - | FC Hradec Králové | 2:1 (1:0) | ||
| 13:30 | FK Mladá Boleslav | - | FC Zlín | 2:1 (1:1) | ||
| 13:45 | Banik Ostrava | - | AC Sparta Praha | 3:2 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
AC Sparta Praha | 15 | 9 | 3 | 3 | 41:16 | 25 | 30 |
| 2 |
|
FC Zbrojovka Brno | 15 | 8 | 5 | 2 | 31:15 | 16 | 29 |
| 3 |
|
Sigma Olomouc | 15 | 9 | 0 | 6 | 34:18 | 16 | 27 |
| 4 |
|
Vysočina Jihlava | 15 | 8 | 2 | 5 | 32:22 | 10 | 26 |
| 5 |
|
FK Mladá Boleslav | 15 | 8 | 2 | 5 | 17:18 | -1 | 26 |
| 6 |
|
FC Zlín | 15 | 7 | 4 | 4 | 49:28 | 21 | 25 |
| 7 |
|
Banik Ostrava | 15 | 7 | 2 | 6 | 29:22 | 7 | 23 |
| 8 |
|
FK Pardubice | 15 | 7 | 2 | 6 | 27:20 | 7 | 23 |
| 9 |
|
1. FC Slovácko | 15 | 6 | 4 | 5 | 20:21 | -1 | 22 |
| 10 |
|
Slavia Praha | 15 | 6 | 3 | 6 | 27:16 | 11 | 21 |
| 11 |
|
Viktoria Plzeň | 15 | 6 | 3 | 6 | 27:27 | 0 | 21 |
| 12 |
|
Dynamo České Budějovice | 15 | 6 | 2 | 7 | 21:30 | -9 | 20 |
| 13 |
|
FK Dukla Praha | 15 | 4 | 4 | 7 | 19:29 | -10 | 16 |
| 14 |
|
MFK Karviná | 15 | 3 | 6 | 6 | 26:38 | -12 | 15 |
| 15 |
|
FC Hradec Králové | 15 | 3 | 3 | 9 | 17:30 | -13 | 12 |
| 16 |
|
FK Viagem Příbram | 15 | 0 | 1 | 14 | 9:76 | -67 | 1 |
| Abstieg |
