 |
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| 16.04.2025 | 08:00 | Minnesota United FC | - | San Jose Earthquakes | 0:2 i.E. | |
| 08:00 | D.C. United | - | Palmeiras | 0:5 | ||
| 08:00 | Charlotte FC | - | Leicester City | 3:1 i.E. | ||
| 08:00 | Seattle Sounders | - | CF Montréal | 6:5 i.E. | ||
| 08:00 | FC Cincinnati | - | Nashville SC | 0:1 | ||
| 08:00 | New York City FC | - | Sporting Kansas City | 4:5 i.E. | ||
| 10:30 | New England Revolution | - | Independiente de La Chorrera | 1:0 | ||
| 10:30 | Club Necaxa | - | Los Angeles FC | 2:3 |
