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| 22.05.2021 | 19:00 | ŠKF Sereď | - | FK Senica | 4:1 (2:0) | |
| 19:00 | FK Pohronie | - | MFK Ružomberok | 1:0 (0:0) | ||
| 19:00 | FC Nitra | - | MFK Zemplín Michalovce | 0:4 (0:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
ŠKF Sereď | 32 | 11 | 8 | 13 | 37:48 | -11 | 41 |
| 2 |
|
MFK Ružomberok | 32 | 10 | 9 | 13 | 41:44 | -3 | 39 |
| 3 |
|
FK Pohronie | 32 | 8 | 14 | 10 | 38:38 | 0 | 38 |
| 4 |
|
MFK Zemplín Michalovce | 32 | 8 | 11 | 13 | 34:53 | -19 | 35 |
| 5 |
|
FK Senica | 32 | 8 | 9 | 15 | 31:51 | -20 | 33 |
| 6 |
|
FC Nitra | 32 | 7 | 6 | 19 | 26:55 | -29 | 27 |
| Relegation | |
| Abstieg |
