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| 15.05.2021 | 17:00 | MFK Ružomberok | - | FC Nitra | 2:0 (0:0) | |
| 17:00 | MFK Zemplín Michalovce | - | ŠKF Sereď | 2:2 (1:1) | ||
| 17:00 | FK Senica | - | FK Pohronie | 0:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
MFK Ružomberok | 31 | 10 | 9 | 12 | 41:43 | -2 | 39 |
| 2 |
|
ŠKF Sereď | 31 | 10 | 8 | 13 | 33:47 | -14 | 38 |
| 3 |
|
FK Pohronie | 31 | 7 | 14 | 10 | 37:38 | -1 | 35 |
| 4 |
|
FK Senica | 31 | 8 | 9 | 14 | 30:47 | -17 | 33 |
| 5 |
|
MFK Zemplín Michalovce | 31 | 7 | 11 | 13 | 30:53 | -23 | 32 |
| 6 |
|
FC Nitra | 31 | 7 | 6 | 18 | 26:51 | -25 | 27 |
| Relegation | |
| Abstieg |
