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| 19.03.2022 | 15:00 | Havre AC | - | SM Caen | 2:4 (0:1) | |
| 15:00 | AJ Auxerre | - | Toulouse FC | 1:2 (0:2) | ||
| 19:00 | AC Ajaccio | - | Nîmes Olympique | 1:0 (0:0) | ||
| 19:00 | EA Guingamp | - | AS Nancy Lorraine | 3:1 (2:0) | ||
| 19:00 | Chamois Niortais | - | US Quevilly-Rouen | 2:0 (1:0) | ||
| 19:00 | Paris FC | - | Pau FC | 1:1 (0:0) | ||
| 19:00 | FC Sochaux | - | Rodez AF | 2:0 (2:0) | ||
| 19:00 | Grenoble Foot 38 | - | SC Bastia | 1:1 (0:0) | ||
| 19:00 | Amiens SC | - | Dijon FCO | 1:1 (0:0) | ||
| 19:00 | USL Dunkerque | - | Valenciennes FC | 1:2 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Toulouse FC | 30 | 18 | 9 | 3 | 69:26 | 43 | 63 |
| 2 |
|
Paris FC | 30 | 16 | 8 | 6 | 43:27 | 16 | 56 |
| 3 |
|
AC Ajaccio | 30 | 16 | 7 | 7 | 26:15 | 11 | 55 |
| 4 |
|
AJ Auxerre | 30 | 15 | 9 | 6 | 47:33 | 14 | 54 |
| 5 |
|
FC Sochaux | 30 | 14 | 9 | 7 | 35:28 | 7 | 51 |
| 6 |
|
Havre AC | 30 | 10 | 11 | 9 | 29:31 | -2 | 41 |
| 7 |
|
SM Caen | 30 | 10 | 9 | 11 | 42:34 | 8 | 39 |
| 8 |
|
Chamois Niortais | 30 | 11 | 6 | 13 | 31:31 | 0 | 39 |
| 9 |
|
Pau FC | 30 | 11 | 6 | 13 | 30:33 | -3 | 39 |
| 10 |
|
Nîmes Olympique | 30 | 11 | 6 | 13 | 35:39 | -4 | 39 |
| 11 |
|
EA Guingamp | 30 | 9 | 12 | 9 | 33:37 | -4 | 39 |
| 12 |
|
Dijon FCO | 30 | 11 | 5 | 14 | 34:37 | -3 | 38 |
| 13 |
|
Amiens SC | 30 | 8 | 13 | 9 | 37:33 | 4 | 37 |
| 14 |
|
SC Bastia | 30 | 8 | 13 | 9 | 30:28 | 2 | 37 |
| 15 |
|
Valenciennes FC | 30 | 8 | 12 | 10 | 30:38 | -8 | 36 |
| 16 |
|
Grenoble Foot 38 | 30 | 9 | 6 | 15 | 23:37 | -14 | 33 |
| 17 |
|
Rodez AF | 30 | 7 | 11 | 12 | 24:34 | -10 | 32 |
| 18 |
|
US Quevilly-Rouen | 30 | 7 | 10 | 13 | 24:40 | -16 | 31 |
| 19 |
|
USL Dunkerque | 30 | 8 | 6 | 16 | 23:37 | -14 | 30 |
| 20 |
|
AS Nancy Lorraine | 30 | 5 | 8 | 17 | 25:52 | -27 | 23 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
