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| 20.04.2022 | 00:00 | Independiente Petrolero | - | Real Tomayapo | 1:1 (1:0) | |
| 00:00 | Universitario de Vinto | - | Bolívar | 1:4 (0:3) | ||
| 02:30 | Blooming | - | Jorge Wilstermann | 3:3 (1:3) | ||
| 21:00 | Royal Pari | - | Always Ready | 5:1 (1:1) | ||
| 21.04.2022 | 00:30 | Club Aurora | - | Oriente Petrolero | 1:1 (0:1) | |
| 02:00 | The Strongest | - | Atlético Palmaflor | 4:1 (0:1) | ||
| 22.04.2022 | 00:15 | CD Guabirá | - | Real Santa Cruz | 1:0 (0:0) | |
| 02:00 | Nacional Potosí | - | Universitario de Sucre | 1:1 (1:1) |
| 1 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Palmaflor | 10 | 6 | 1 | 3 | 11:13 | -2 | 19 |
| 2 |
|
The Strongest | 10 | 5 | 3 | 2 | 17:8 | 9 | 18 |
| 3 |
|
Nacional Potosí | 10 | 4 | 3 | 3 | 19:14 | 5 | 15 |
| 4 |
|
Universitario de Sucre | 10 | 4 | 3 | 3 | 15:12 | 3 | 15 |
| 5 |
|
Oriente Petrolero | 10 | 4 | 2 | 4 | 14:13 | 1 | 14 |
| 6 |
|
Club Aurora | 10 | 2 | 4 | 4 | 10:13 | -3 | 10 |
| 7 |
|
Real Santa Cruz | 10 | 2 | 2 | 6 | 11:15 | -4 | 8 |
| 8 |
|
CD Guabirá | 10 | 2 | 2 | 6 | 9:18 | -9 | 8 |
| 2 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bolívar | 10 | 7 | 1 | 2 | 30:4 | 26 | 22 |
| 2 |
|
Blooming | 10 | 6 | 2 | 2 | 18:21 | -3 | 20 |
| 3 |
|
Royal Pari | 10 | 4 | 3 | 3 | 20:17 | 3 | 15 |
| 4 |
|
Real Tomayapo | 10 | 3 | 4 | 3 | 9:13 | -4 | 13 |
| 5 |
|
Jorge Wilstermann | 10 | 3 | 3 | 4 | 10:11 | -1 | 12 |
| 6 |
|
Always Ready | 10 | 3 | 3 | 4 | 13:16 | -3 | 12 |
| 7 |
|
Independiente Petrolero | 10 | 2 | 4 | 4 | 12:17 | -5 | 10 |
| 8 |
|
Universitario de Vinto | 10 | 2 | 2 | 6 | 10:23 | -13 | 8 |
| Playoffs | |
| Playoffs |
