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| 17.03.2023 | 12:00 | Metalist Kharkiv | - | FK Oleksandriya | 0:0 (0:0) | |
| 18.03.2023 | 12:00 | Vorskla Poltava | - | Metalist 1925 Kharkiv | 0:0 (0:0) | |
| 13:00 | Dinamo Kiev | - | Zorya Lugansk | 0:1 (0:0) | ||
| 13:00 | FK Lviv | - | Kryvbas Kryvyi Rih | 2:2 (0:1) | ||
| 14:00 | NK Veres | - | SK Dnipro-1 | 0:1 (0:1) | ||
| 19.03.2023 | 12:00 | Inhulets Petrove | - | Chernomorets Odessa | 1:2 (0:2) | |
| 13:00 | Kolos Kovalivka | - | FC Mynai | 0:1 (0:1) | ||
| 14:00 | Shakhtar Donetsk | - | Rukh Lviv | 2:0 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Shakhtar Donetsk | 18 | 14 | 3 | 1 | 47:13 | 34 | 45 |
| 2 |
|
SK Dnipro-1 | 18 | 12 | 4 | 2 | 35:14 | 21 | 40 |
| 3 |
|
Zorya Lugansk | 18 | 11 | 4 | 3 | 39:25 | 14 | 37 |
| 4 |
|
Dinamo Kiev | 18 | 10 | 3 | 5 | 25:16 | 9 | 33 |
| 5 |
|
FK Oleksandriya | 18 | 7 | 8 | 3 | 30:26 | 4 | 29 |
| 6 |
|
Kolos Kovalivka | 18 | 6 | 5 | 7 | 15:20 | -5 | 23 |
| 7 |
|
Inhulets Petrove | 18 | 6 | 4 | 8 | 18:21 | -3 | 22 |
| 8 |
|
Kryvbas Kryvyi Rih | 18 | 6 | 4 | 8 | 14:21 | -7 | 22 |
| 9 |
|
Metalist 1925 Kharkiv | 18 | 4 | 9 | 5 | 17:28 | -11 | 21 |
| 10 |
|
Vorskla Poltava | 18 | 5 | 5 | 8 | 22:25 | -3 | 20 |
| 11 |
|
NK Veres | 18 | 5 | 3 | 10 | 20:26 | -6 | 18 |
| 12 |
|
Chernomorets Odessa | 18 | 4 | 6 | 8 | 16:23 | -7 | 18 |
| 13 |
|
FC Mynai | 18 | 4 | 6 | 8 | 13:21 | -8 | 18 |
| 14 |
|
Rukh Lviv | 18 | 4 | 5 | 9 | 19:27 | -8 | 17 |
| 15 |
|
Metalist Kharkiv | 18 | 4 | 5 | 9 | 17:27 | -10 | 17 |
| 16 |
|
FK Lviv | 18 | 3 | 4 | 11 | 14:28 | -14 | 13 |
| Champions League Quali. | |
| Champions League Quali. | |
| Europa Conference League Quali. |
