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| 01.05.2022 | 17:00 | Vojvodina | - | Crvena Zvezda | 0:3 (0:2) | |
| 18:30 | TSC Bačka Topola | - | FK Voždovac | 1:1 (0:0) | ||
| 19:05 | FK Napredak | - | Partizan | 0:3 (0:1) | ||
| 02.05.2022 | 18:30 | FK Čukarički | - | Radnički Niš | 0:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Crvena Zvezda | 34 | 29 | 4 | 1 | 87:17 | 70 | 91 |
| 2 |
|
Partizan | 34 | 28 | 5 | 1 | 78:12 | 66 | 89 |
| 3 |
|
FK Čukarički | 34 | 14 | 13 | 7 | 51:34 | 17 | 55 |
| 4 |
|
FK Voždovac | 34 | 13 | 9 | 12 | 47:39 | 8 | 48 |
| 5 |
|
Radnički Niš | 34 | 11 | 15 | 8 | 37:33 | 4 | 48 |
| 6 |
|
TSC Bačka Topola | 34 | 12 | 9 | 13 | 49:52 | -3 | 45 |
| 7 |
|
Vojvodina | 34 | 12 | 6 | 16 | 41:46 | -5 | 42 |
| 8 |
|
FK Napredak | 34 | 10 | 7 | 17 | 31:48 | -17 | 37 |
| Champions League Quali. | |
| Europa Conference League Quali. |
