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| 29.03.1981 | Westfalia Herne | - | Hammer SpVg | 1:1 | ||
| VfB Rheine | - | SV Holzwickede | 1:2 | |||
| STV Horst-Emscher | - | 1. FC Paderborn | 3:2 | |||
| TuS Schloß-Neuhaus | - | SuS Hüsten 09 | 1:1 | |||
| Hellweg Lütgendortmund | - | VfB Waltrop | 3:3 | |||
| Bünder SV | - | Eintracht Recklinghausen | 0:1 | |||
| VfL Gevelsberg | - | DSC Wanne-Eickel | 1:0 | |||
| FC Gütersloh | - | Sportfreunde Siegen | 1:0 | |||
| Teutonia Lippstadt | - | VfB Altena | 5:1 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VfL Gevelsberg | 28 | 15 | 9 | 4 | 58:32 | 26 | 39:17 |
| 2 |
|
VfB Rheine | 28 | 15 | 7 | 6 | 59:34 | 25 | 37:19 |
| 3 |
|
FC Gütersloh | 28 | 15 | 6 | 7 | 51:31 | 20 | 36:20 |
| 4 |
|
1. FC Paderborn | 28 | 16 | 4 | 8 | 53:34 | 19 | 36:20 |
| 5 |
|
Hammer SpVg | 28 | 13 | 7 | 8 | 54:42 | 12 | 33:23 |
| 6 |
|
Sportfreunde Siegen | 28 | 13 | 7 | 8 | 46:37 | 9 | 33:23 |
| 7 |
|
DSC Wanne-Eickel | 28 | 11 | 10 | 7 | 61:41 | 20 | 32:24 |
| 8 |
|
TuS Schloß-Neuhaus | 28 | 13 | 6 | 9 | 49:39 | 10 | 32:24 |
| 9 |
|
VfB Waltrop | 28 | 10 | 8 | 10 | 44:44 | 0 | 28:28 |
| 10 |
|
Westfalia Herne | 28 | 8 | 12 | 8 | 38:41 | -3 | 28:28 |
| 11 |
|
SuS Hüsten 09 | 28 | 8 | 10 | 10 | 35:40 | -5 | 26:30 |
| 12 |
|
Teutonia Lippstadt | 28 | 8 | 8 | 12 | 47:43 | 4 | 24:32 |
| 13 |
|
Hellweg Lütgendortmund | 28 | 7 | 10 | 11 | 34:45 | -11 | 24:32 |
| 14 |
|
Eintracht Recklinghausen | 28 | 6 | 9 | 13 | 38:59 | -21 | 21:35 |
| 15 |
|
STV Horst-Emscher | 28 | 7 | 7 | 14 | 33:65 | -32 | 21:35 |
| 16 |
|
VfB Altena | 28 | 5 | 9 | 14 | 30:61 | -31 | 19:37 |
| 17 |
|
Bünder SV | 28 | 6 | 6 | 16 | 34:57 | -23 | 18:38 |
| 18 |
|
SV Holzwickede | 28 | 4 | 9 | 15 | 30:49 | -19 | 17:39 |
