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| 15.03.1981 | VfL Gevelsberg | - | Hammer SpVg | 2:1 | ||
| FC Gütersloh | - | SV Holzwickede | 1:0 | |||
| Westfalia Herne | - | 1. FC Paderborn | 0:0 | |||
| VfB Rheine | - | Teutonia Lippstadt | 2:1 | |||
| SuS Hüsten 09 | - | VfB Waltrop | 2:1 | |||
| TuS Schloß-Neuhaus | - | Eintracht Recklinghausen | 2:0 | |||
| Hellweg Lütgendortmund | - | DSC Wanne-Eickel | 1:1 | |||
| Bünder SV | - | Sportfreunde Siegen | 2:3 | |||
| STV Horst-Emscher | - | VfB Altena | 2:0 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VfB Rheine | 26 | 15 | 7 | 4 | 58:29 | 29 | 37:15 |
| 2 |
|
VfL Gevelsberg | 26 | 14 | 8 | 4 | 55:30 | 25 | 36:16 |
| 3 |
|
FC Gütersloh | 26 | 14 | 6 | 6 | 50:28 | 22 | 34:18 |
| 4 |
|
1. FC Paderborn | 26 | 15 | 4 | 7 | 48:31 | 17 | 34:18 |
| 5 |
|
Sportfreunde Siegen | 26 | 13 | 6 | 7 | 44:34 | 10 | 32:20 |
| 6 |
|
DSC Wanne-Eickel | 26 | 10 | 10 | 6 | 59:39 | 20 | 30:22 |
| 7 |
|
TuS Schloß-Neuhaus | 26 | 13 | 4 | 9 | 48:38 | 10 | 30:22 |
| 8 |
|
Hammer SpVg | 26 | 12 | 6 | 8 | 50:41 | 9 | 30:22 |
| 9 |
|
VfB Waltrop | 26 | 10 | 6 | 10 | 41:41 | 0 | 26:26 |
| 10 |
|
Westfalia Herne | 26 | 8 | 10 | 8 | 37:40 | -3 | 26:26 |
| 11 |
|
SuS Hüsten 09 | 26 | 7 | 9 | 10 | 30:38 | -8 | 23:29 |
| 12 |
|
Hellweg Lütgendortmund | 26 | 7 | 9 | 10 | 31:40 | -9 | 23:29 |
| 13 |
|
Teutonia Lippstadt | 26 | 7 | 7 | 12 | 42:42 | 0 | 21:31 |
| 14 |
|
VfB Altena | 26 | 5 | 9 | 12 | 28:52 | -24 | 19:33 |
| 15 |
|
Bünder SV | 26 | 6 | 6 | 14 | 33:54 | -21 | 18:34 |
| 16 |
|
STV Horst-Emscher | 26 | 6 | 6 | 14 | 30:63 | -33 | 18:34 |
| 17 |
|
Eintracht Recklinghausen | 26 | 4 | 9 | 13 | 35:59 | -24 | 17:35 |
| 18 |
|
SV Holzwickede | 26 | 3 | 8 | 15 | 28:48 | -20 | 14:38 |
