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| 09.04.2022 | 15:30 | AJ Auxerre | - | AS Nancy Lorraine | 2:3 (1:2) | |
| 10.04.2022 | 15:00 | FC Sochaux | - | Dijon FCO | 2:0 (1:0) | |
| 15:00 | FC Lyon | - | FC Annecy | 1:1 (0:0) | ||
| 15:00 | FC Metz | - | SAS Épinal | 0:2 (0:2) | ||
| 15:00 | Racing Besançon | - | RC Strasbourg | 2:5 (1:2) | ||
| 15:00 | FC Bourg-Péronnas | - | ASPTT Dijon | 1:2 (1:1) | ||
| 20.04.2022 | 15:00 | Olympique Lyon | - | FC Mulhouse | 4:0 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RC Strasbourg | 23 | 19 | 1 | 3 | 72:23 | 49 | 58 |
| 2 |
|
Olympique Lyon | 23 | 18 | 3 | 2 | 70:17 | 53 | 57 |
| 3 |
|
AS Nancy Lorraine | 23 | 15 | 4 | 4 | 59:26 | 33 | 49 |
| 4 |
|
AJ Auxerre | 23 | 14 | 3 | 6 | 61:25 | 36 | 45 |
| 5 |
|
FC Sochaux | 23 | 14 | 3 | 6 | 59:37 | 22 | 45 |
| 6 |
|
FC Metz | 23 | 13 | 2 | 8 | 45:26 | 19 | 41 |
| 7 |
|
FC Annecy | 23 | 9 | 3 | 11 | 33:40 | -7 | 30 |
| 8 |
|
FC Lyon | 23 | 7 | 6 | 10 | 29:39 | -10 | 27 |
| 9 |
|
Dijon FCO | 23 | 7 | 4 | 12 | 29:45 | -16 | 25 |
| 10 |
|
FC Mulhouse | 23 | 7 | 2 | 14 | 26:52 | -26 | 23 |
| 11 |
|
FC Bourg-Péronnas | 23 | 6 | 4 | 13 | 26:51 | -25 | 22 |
| 12 |
|
ASPTT Dijon | 23 | 5 | 5 | 13 | 24:55 | -31 | 20 |
| 13 |
|
SAS Épinal | 23 | 2 | 4 | 17 | 15:61 | -46 | 10 |
| 14 |
|
Racing Besançon | 23 | 1 | 4 | 18 | 20:71 | -51 | 7 |
| Meisterrunde | |
| Qualifikation möglich | |
| Abstieg |
