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| 11.05.2022 | 00:00 | Universitario de Vinto | - | Royal Pari | 3:2 (1:2) | |
| 02:00 | CD Guabirá | - | Atlético Palmaflor | 3:0 (1:0) | ||
| 12.05.2022 | 00:00 | Jorge Wilstermann | - | Always Ready | 1:0 (1:0) | |
| 02:00 | Universitario de Sucre | - | Oriente Petrolero | 1:1 (1:0) | ||
| 02:00 | Nacional Potosí | - | The Strongest | 1:1 (1:1) | ||
| 21:00 | Club Aurora | - | Real Santa Cruz | 2:4 (1:2) | ||
| 13.05.2022 | 02:00 | Blooming | - | Independiente Petrolero | 4:0 (1:0) | |
| 02:00 | Bolívar | - | Real Tomayapo | 1:0 (1:0) |
| 1 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
The Strongest | 14 | 6 | 5 | 3 | 20:11 | 9 | 23 |
| 2 |
|
Oriente Petrolero | 14 | 6 | 4 | 4 | 19:16 | 3 | 22 |
| 3 |
|
Atlético Palmaflor | 14 | 7 | 1 | 6 | 13:19 | -6 | 22 |
| 4 |
|
Nacional Potosí | 14 | 5 | 4 | 5 | 24:20 | 4 | 19 |
| 5 |
|
Club Aurora | 14 | 4 | 5 | 5 | 16:17 | -1 | 17 |
| 6 |
|
Universitario de Sucre | 14 | 4 | 4 | 6 | 16:18 | -2 | 16 |
| 7 |
|
CD Guabirá | 14 | 4 | 3 | 7 | 16:21 | -5 | 15 |
| 8 |
|
Real Santa Cruz | 14 | 4 | 3 | 7 | 19:25 | -6 | 15 |
| 2 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bolívar | 14 | 11 | 1 | 2 | 37:6 | 31 | 34 |
| 2 |
|
Blooming | 14 | 7 | 3 | 4 | 25:26 | -1 | 24 |
| 3 |
|
Royal Pari | 14 | 5 | 4 | 5 | 30:25 | 5 | 19 |
| 4 |
|
Jorge Wilstermann | 14 | 4 | 5 | 5 | 14:15 | -1 | 17 |
| 5 |
|
Real Tomayapo | 14 | 4 | 5 | 5 | 12:21 | -9 | 17 |
| 6 |
|
Always Ready | 14 | 4 | 4 | 6 | 20:20 | 0 | 16 |
| 7 |
|
Independiente Petrolero | 14 | 4 | 4 | 6 | 17:26 | -9 | 16 |
| 8 |
|
Universitario de Vinto | 14 | 4 | 3 | 7 | 16:28 | -12 | 15 |
| Playoffs | |
| Playoffs |
