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| 01.10.2021 | 18:30 | SV Seligenporten | - | ATSV Erlangen | 1:4 (1:3) | |
| 02.10.2021 | 14:00 | Eintracht Bamberg | - | TSV Karlburg | 0:1 (0:0) | |
| 15:00 | SpVgg Bayern Hof | - | DJK Ammerthal | 0:2 (0:0) | ||
| 15:00 | Würzburger FV | - | ASV Cham | 1:0 (1:0) | ||
| 16:00 | 1. FC Sand | - | Vatan Spor Aschaffenburg | 0:0 (0:0) | ||
| 16:00 | TSV Abtswind | - | SpVgg Ansbach | 0:2 (0:1) | ||
| 16:00 | TSV Großbardorf | - | DJK Gebenbach | 0:5 (0:3) | ||
| 03.10.2021 | 11:00 | ASV Neumarkt | - | 1. SC Feucht | 2:0 (2:0) | |
| 15:00 | DJK Bamberg | - | DJK Vilzing | 2:5 (2:3) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SpVgg Ansbach | 14 | 11 | 1 | 2 | 32:8 | 24 | 34 |
| 2 |
|
Eintracht Bamberg | 14 | 10 | 2 | 2 | 38:9 | 29 | 32 |
| 3 |
|
DJK Vilzing | 14 | 10 | 1 | 3 | 33:14 | 19 | 31 |
| 4 |
|
DJK Ammerthal | 14 | 9 | 2 | 3 | 37:19 | 18 | 29 |
| 5 |
|
ASV Neumarkt | 14 | 9 | 2 | 3 | 30:16 | 14 | 29 |
| 6 |
|
ATSV Erlangen | 14 | 9 | 2 | 3 | 28:16 | 12 | 29 |
| 7 |
|
1. SC Feucht | 14 | 7 | 3 | 4 | 22:16 | 6 | 24 |
| 8 |
|
TSV Abtswind | 14 | 7 | 2 | 5 | 20:16 | 4 | 23 |
| 9 |
|
DJK Bamberg | 14 | 6 | 1 | 7 | 22:24 | -2 | 19 |
| 10 |
|
SpVgg Bayern Hof | 14 | 5 | 2 | 7 | 29:35 | -6 | 17 |
| 11 |
|
DJK Gebenbach | 14 | 5 | 1 | 8 | 30:33 | -3 | 16 |
| 12 |
|
TSV Großbardorf | 14 | 5 | 1 | 8 | 20:29 | -9 | 16 |
| 13 |
|
TSV Karlburg | 14 | 3 | 6 | 5 | 11:20 | -9 | 15 |
| 14 |
|
1. FC Sand | 14 | 3 | 4 | 7 | 13:27 | -14 | 13 |
| 15 |
|
Würzburger FV | 14 | 3 | 1 | 10 | 13:33 | -20 | 10 |
| 16 |
|
ASV Cham | 14 | 2 | 2 | 10 | 16:35 | -19 | 8 |
| 17 |
|
Vatan Spor Aschaffenburg | 14 | 2 | 2 | 10 | 11:31 | -20 | 8 |
| 18 |
|
SV Seligenporten | 14 | 2 | 1 | 11 | 16:40 | -24 | 7 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
