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| 11.05.2021 | 16:00 | Konyaspor | - | Trabzonspor | 1:1 (0:0) | |
| 19:30 | Alanyaspor | - | BB Erzurumspor | 2:3 (2:1) | ||
| 19:30 | Beşiktaş | - | Fatih Karagümrük SK | 1:2 (0:1) | ||
| 19:30 | Denizlispor | - | Galatasaray | 1:4 (0:2) | ||
| 19:30 | Fenerbahçe | - | Sivasspor | 1:2 (0:1) | ||
| 19:30 | Gaziantep FK | - | Çaykur Rizespor | 4:5 (0:3) | ||
| 19:30 | Gençlerbirliği | - | Göztepe | 5:3 (1:2) | ||
| 19:30 | İstanbul Başakşehir | - | Kayserispor | 0:0 (0:0) | ||
| 19:30 | Kasımpaşa SK | - | MKE Ankaragücü | 3:1 (2:0) | ||
| 19:30 | Yeni Malatyaspor | - | Hatayspor | 1:1 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Beşiktaş | 39 | 25 | 6 | 8 | 87:43 | 44 | 81 |
| 2 |
|
Galatasaray | 39 | 25 | 6 | 8 | 77:35 | 42 | 81 |
| 3 |
|
Fenerbahçe | 39 | 24 | 7 | 8 | 70:40 | 30 | 79 |
| 4 |
|
Trabzonspor | 39 | 18 | 14 | 7 | 48:36 | 12 | 68 |
| 5 |
|
Sivasspor | 39 | 15 | 17 | 7 | 52:42 | 10 | 62 |
| 6 |
|
Hatayspor | 39 | 17 | 10 | 12 | 62:52 | 10 | 61 |
| 7 |
|
Alanyaspor | 39 | 16 | 9 | 14 | 57:45 | 12 | 57 |
| 8 |
|
Fatih Karagümrük SK | 39 | 15 | 12 | 12 | 59:51 | 8 | 57 |
| 9 |
|
Gaziantep FK | 39 | 14 | 13 | 12 | 58:51 | 7 | 55 |
| 10 |
|
Göztepe | 39 | 13 | 12 | 14 | 58:57 | 1 | 51 |
| 11 |
|
Konyaspor | 39 | 12 | 13 | 14 | 49:48 | 1 | 49 |
| 12 |
|
Çaykur Rizespor | 39 | 12 | 12 | 15 | 53:67 | -14 | 48 |
| 13 |
|
Kasımpaşa SK | 39 | 12 | 10 | 17 | 46:55 | -9 | 46 |
| 14 |
|
Yeni Malatyaspor | 39 | 10 | 15 | 14 | 48:50 | -2 | 45 |
| 15 |
|
İstanbul Başakşehir | 39 | 11 | 12 | 16 | 41:55 | -14 | 45 |
| 16 |
|
Antalyaspor | 39 | 9 | 16 | 14 | 41:55 | -14 | 43 |
| 17 |
|
Kayserispor | 39 | 9 | 14 | 16 | 34:50 | -16 | 41 |
| 18 |
|
BB Erzurumspor | 40 | 10 | 10 | 20 | 44:68 | -24 | 40 |
| 19 |
|
MKE Ankaragücü | 39 | 10 | 8 | 21 | 46:64 | -18 | 38 |
| 20 |
|
Gençlerbirliği | 39 | 10 | 8 | 21 | 43:74 | -31 | 38 |
| 21 |
|
Denizlispor | 39 | 6 | 10 | 23 | 37:72 | -35 | 28 |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Abstieg |
