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| 16.04.2021 | 15:00 | Gençlerbirliği | - | Sivasspor | 2:3 (2:0) | |
| 15:00 | Konyaspor | - | Kayserispor | 0:0 (0:0) | ||
| 18:00 | Antalyaspor | - | Çaykur Rizespor | 2:3 (1:2) | ||
| 18:00 | Beşiktaş | - | MKE Ankaragücü | 2:2 (1:0) | ||
| 17.04.2021 | 12:30 | Denizlispor | - | BB Erzurumspor | 2:3 (0:1) | |
| 15:00 | Trabzonspor | - | Hatayspor | 1:1 (1:0) | ||
| 15:00 | Yeni Malatyaspor | - | Alanyaspor | 1:0 (0:0) | ||
| 18:00 | Göztepe | - | Galatasaray | 1:3 (1:2) | ||
| 18.04.2021 | 15:00 | Gaziantep FK | - | Kasımpaşa SK | 2:2 (0:1) | |
| 18:00 | İstanbul Başakşehir | - | Fenerbahçe | 1:2 (1:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Beşiktaş | 33 | 22 | 5 | 6 | 72:35 | 37 | 71 |
| 2 |
|
Fenerbahçe | 34 | 21 | 6 | 7 | 61:34 | 27 | 69 |
| 3 |
|
Galatasaray | 33 | 20 | 5 | 8 | 65:32 | 33 | 65 |
| 4 |
|
Trabzonspor | 34 | 16 | 11 | 7 | 41:32 | 9 | 59 |
| 5 |
|
Alanyaspor | 34 | 15 | 7 | 12 | 52:37 | 15 | 52 |
| 6 |
|
Gaziantep FK | 33 | 13 | 12 | 8 | 49:39 | 10 | 51 |
| 7 |
|
Hatayspor | 33 | 14 | 8 | 11 | 54:41 | 13 | 50 |
| 8 |
|
Sivasspor | 33 | 12 | 14 | 7 | 47:40 | 7 | 50 |
| 9 |
|
Fatih Karagümrük SK | 33 | 13 | 10 | 10 | 48:39 | 9 | 49 |
| 10 |
|
Göztepe | 34 | 12 | 10 | 12 | 50:47 | 3 | 46 |
| 11 |
|
Antalyaspor | 34 | 9 | 15 | 10 | 34:44 | -10 | 42 |
| 12 |
|
Konyaspor | 33 | 10 | 11 | 12 | 39:40 | -1 | 41 |
| 13 |
|
Çaykur Rizespor | 33 | 9 | 12 | 12 | 39:51 | -12 | 39 |
| 14 |
|
Yeni Malatyaspor | 33 | 8 | 13 | 12 | 40:45 | -5 | 37 |
| 15 |
|
MKE Ankaragücü | 33 | 10 | 7 | 16 | 41:53 | -12 | 37 |
| 16 |
|
Kasımpaşa SK | 34 | 9 | 10 | 15 | 37:50 | -13 | 37 |
| 17 |
|
Kayserispor | 33 | 8 | 10 | 15 | 24:41 | -17 | 34 |
| 18 |
|
İstanbul Başakşehir | 33 | 8 | 9 | 16 | 36:53 | -17 | 33 |
| 19 |
|
BB Erzurumspor | 34 | 7 | 10 | 17 | 35:58 | -23 | 31 |
| 20 |
|
Gençlerbirliği | 33 | 8 | 7 | 18 | 32:58 | -26 | 31 |
| 21 |
|
Denizlispor | 33 | 6 | 8 | 19 | 31:58 | -27 | 26 |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Abstieg |
