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| H | FC Winterthur | - | FC Basel | 1:2 (1:1) | ||
| R | FC Basel | - | FC Winterthur | 3:0 (1:0) | ||
| H: 28.05.2022 13:00 | R: 04.06.2022 16:30 | Sieger: FC Basel | ||||
| H | FC Zürich | - | Team Vaud Lausanne | 5:0 (2:0) | ||
| R | Team Vaud Lausanne | - | FC Zürich | 2:3 (0:2) | ||
| H: 28.05.2022 14:00 | R: 04.06.2022 14:30 | Sieger: FC Zürich | ||||
| H | FCO St. Gallen/Wil | - | Servette FC | 2:1 (1:0) | ||
| R | Servette FC | - | FCO St. Gallen/Wil | 3:1 (0:0) | ||
| H: 28.05.2022 14:00 | R: 04.06.2022 14:00 | Sieger: Servette FC | ||||
| H | Team Aargau | - | BSC Young Boys | 1:5 (0:3) | ||
| R | BSC Young Boys | - | Team Aargau | 3:0 (1:0) | ||
| H: 28.05.2022 16:00 | R: 04.06.2022 14:00 | Sieger: BSC Young Boys | ||||
