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| 09.05.1981 | 18:30 | FC Nordstern Basel | - | FC Zürich | 1:2 (0:1) | |
| 20:00 | Servette FC | - | FC Basel | 2:1 (0:1) | ||
| 20:00 | Lausanne Sports | - | CS Chênois | 4:1 (0:0) | ||
| 20:00 | FC Luzern | - | FC Chiasso | 1:2 (1:1) | ||
| 20:00 | Neuchâtel Xamax FC | - | FC Sion | 2:1 (0:0) | ||
| 20:00 | Grasshopper Club Zürich | - | BSC Young Boys | 2:2 (0:2) | ||
| 20:30 | AC Bellinzona | - | FC St. Gallen | 2:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Zürich | 22 | 16 | 2 | 4 | 48:27 | 21 | 34:10 |
| 2 |
|
Grasshopper Club Zürich | 22 | 10 | 10 | 2 | 41:20 | 21 | 30:14 |
| 3 |
|
Neuchâtel Xamax FC | 22 | 12 | 5 | 5 | 39:24 | 15 | 29:15 |
| 4 |
|
BSC Young Boys | 22 | 9 | 9 | 4 | 39:30 | 9 | 27:17 |
| 5 |
|
Lausanne Sports | 22 | 11 | 4 | 7 | 36:25 | 11 | 26:18 |
| 6 |
|
FC Basel | 22 | 9 | 6 | 7 | 40:36 | 4 | 24:20 |
| 7 |
|
Servette FC | 22 | 6 | 9 | 7 | 32:32 | 0 | 21:23 |
| 8 |
|
FC Sion | 22 | 7 | 7 | 8 | 30:32 | -2 | 21:23 |
| 9 |
|
FC Luzern | 22 | 6 | 7 | 9 | 32:36 | -4 | 19:25 |
| 10 |
|
FC St. Gallen | 22 | 6 | 6 | 10 | 32:38 | -6 | 18:26 |
| 11 |
|
FC Chiasso | 22 | 4 | 8 | 10 | 23:39 | -16 | 16:28 |
| 12 |
|
AC Bellinzona | 22 | 6 | 4 | 12 | 21:37 | -16 | 16:28 |
| 13 |
|
FC Nordstern Basel | 22 | 4 | 6 | 12 | 22:35 | -13 | 14:30 |
| 14 |
|
CS Chênois | 22 | 2 | 9 | 11 | 19:43 | -24 | 13:31 |
| Champions League | |
| Europa League | |
| Abstieg |
