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| 02.05.1981 | 17:30 | FC St. Gallen | - | FC Luzern | 5:4 (4:3) | |
| 20:00 | FC Zürich | - | AC Bellinzona | 3:1 (1:1) | ||
| 20:00 | BSC Young Boys | - | Lausanne Sports | 2:4 (0:1) | ||
| 20:00 | FC Basel | - | Neuchâtel Xamax FC | 1:2 (1:0) | ||
| 20:15 | FC Sion | - | Grasshopper Club Zürich | 2:2 (0:0) | ||
| 20:30 | CS Chênois | - | FC Nordstern Basel | 0:1 (0:0) | ||
| 20:30 | FC Chiasso | - | Servette FC | 1:1 (1:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Zürich | 21 | 15 | 2 | 4 | 46:26 | 20 | 32:10 |
| 2 |
|
Grasshopper Club Zürich | 21 | 10 | 9 | 2 | 39:18 | 21 | 29:13 |
| 3 |
|
Neuchâtel Xamax FC | 21 | 11 | 5 | 5 | 37:23 | 14 | 27:15 |
| 4 |
|
BSC Young Boys | 21 | 9 | 8 | 4 | 37:28 | 9 | 26:16 |
| 5 |
|
Lausanne Sports | 21 | 10 | 4 | 7 | 32:24 | 8 | 24:18 |
| 6 |
|
FC Basel | 21 | 9 | 6 | 6 | 39:34 | 5 | 24:18 |
| 7 |
|
FC Sion | 21 | 7 | 7 | 7 | 29:30 | -1 | 21:21 |
| 8 |
|
Servette FC | 21 | 5 | 9 | 7 | 30:31 | -1 | 19:23 |
| 9 |
|
FC Luzern | 21 | 6 | 7 | 8 | 31:34 | -3 | 19:23 |
| 10 |
|
FC St. Gallen | 21 | 6 | 6 | 9 | 32:36 | -4 | 18:24 |
| 11 |
|
FC Nordstern Basel | 21 | 4 | 6 | 11 | 21:33 | -12 | 14:28 |
| 12 |
|
FC Chiasso | 21 | 3 | 8 | 10 | 21:38 | -17 | 14:28 |
| 13 |
|
AC Bellinzona | 21 | 5 | 4 | 12 | 19:37 | -18 | 14:28 |
| 14 |
|
CS Chênois | 21 | 2 | 9 | 10 | 18:39 | -21 | 13:29 |
| Champions League | |
| Europa League | |
| Abstieg |
