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| 19.05.2021 | 11:00 | FK Krasnodar | - | Rubin Kazan | 1:1 (1:0) | |
| 13:00 | FK Rostov | - | Lokomotiv Moskva | 1:0 (1:0) | ||
| 13:00 | Spartak Moskva | - | FK Strogino Moskva | 4:2 (2:2) | ||
| 15:00 | Akhmat Grozny | - | CSKA Moskva | 0:3 (0:0) | ||
| 15:30 | PFC Sochi | - | Zenit St. Petersburg | 0:1 (0:1) |
| » Tabelle | Heim | Auswärts | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moskva | 26 | 21 | 1 | 4 | 76:26 | 50 | 64 |
| 2 |
|
FK Krasnodar | 26 | 19 | 4 | 3 | 56:20 | 36 | 61 |
| 3 |
|
Zenit St. Petersburg | 26 | 19 | 2 | 5 | 66:27 | 39 | 59 |
| 4 |
|
Spartak Moskva | 26 | 16 | 6 | 4 | 52:26 | 26 | 54 |
| 5 |
|
Lokomotiv Moskva | 26 | 14 | 5 | 7 | 46:21 | 25 | 47 |
| 6 |
|
Akhmat Grozny | 26 | 13 | 6 | 7 | 46:42 | 4 | 45 |
| 7 |
|
FK Rostov | 26 | 10 | 7 | 9 | 42:37 | 5 | 37 |
| 8 |
|
Rubin Kazan | 26 | 9 | 8 | 9 | 30:30 | 0 | 35 |
| 9 |
|
FK Strogino Moskva | 26 | 9 | 4 | 13 | 43:51 | -8 | 31 |
| 10 |
|
PFC Sochi | 26 | 7 | 8 | 11 | 29:33 | -4 | 29 |
