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| 12.05.2021 | 11:00 | Zenit St. Petersburg | - | FK Rostov | 1:3 (0:0) | |
| 12:00 | Rubin Kazan | - | Spartak Moskva | 2:2 (2:1) | ||
| 12:00 | FK Strogino Moskva | - | Akhmat Grozny | 6:1 (1:1) | ||
| 13:00 | CSKA Moskva | - | PFC Sochi | 2:0 (1:0) | ||
| 15:30 | Lokomotiv Moskva | - | FK Krasnodar | 1:1 (0:0) |
| » Tabelle | Heim | Auswärts | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moskva | 25 | 20 | 1 | 4 | 73:26 | 47 | 61 |
| 2 |
|
FK Krasnodar | 25 | 19 | 3 | 3 | 55:19 | 36 | 60 |
| 3 |
|
Zenit St. Petersburg | 25 | 18 | 2 | 5 | 65:27 | 38 | 56 |
| 4 |
|
Spartak Moskva | 25 | 15 | 6 | 4 | 48:24 | 24 | 51 |
| 5 |
|
Lokomotiv Moskva | 25 | 14 | 5 | 6 | 46:20 | 26 | 47 |
| 6 |
|
Akhmat Grozny | 25 | 13 | 6 | 6 | 46:39 | 7 | 45 |
| 7 |
|
FK Rostov | 25 | 9 | 7 | 9 | 41:37 | 4 | 34 |
| 8 |
|
Rubin Kazan | 25 | 9 | 7 | 9 | 29:29 | 0 | 34 |
| 9 |
|
FK Strogino Moskva | 25 | 9 | 4 | 12 | 41:47 | -6 | 31 |
| 10 |
|
PFC Sochi | 25 | 7 | 8 | 10 | 29:32 | -3 | 29 |
