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| 23.04.2022 | 14:00 | Viktoria Aschaffenburg | - | SV Schalding-Heining | 4:0 (2:0) | |
| 14:00 | 1. FC Schweinfurt 05 | - | SpVgg Unterhaching | 0:2 (0:0) | ||
| 14:00 | FC Augsburg II | - | FV Illertissen | 4:0 (1:0) | ||
| 14:00 | SpVgg Bayreuth | - | TSV 1860 Rosenheim | 0:4 (0:1) | ||
| 14:00 | SpVgg Greuther Fürth II | - | FC Memmingen | 0:1 (0:0) | ||
| 14:00 | TSV Aubstadt | - | VfB Eichstätt | 4:0 (3:0) | ||
| 14:00 | TSV 1896 Rain | - | Bayern München II | 2:4 (1:2) | ||
| 14:00 | Wacker Burghausen | - | SC Eltersdorf | 3:0 (2:0) | ||
| 14:30 | 1. FC Nürnberg II | - | SV Heimstetten | 0:0 (0:0) | ||
| 17:00 | TSV Buchbach | - | FC Pipinsried | 0:2 (0:1) |
| » Tabelle | Heim | Auswärts | Hinrunde | Rückrunde | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SpVgg Bayreuth | 34 | 27 | 3 | 4 | 93:32 | 61 | 84 |
| 2 |
|
Bayern München II | 34 | 24 | 7 | 3 | 107:42 | 65 | 79 |
| 3 |
|
1. FC Schweinfurt 05 | 34 | 17 | 10 | 7 | 90:44 | 46 | 61 |
| 4 |
|
SpVgg Unterhaching | 34 | 17 | 8 | 9 | 69:55 | 14 | 59 |
| 5 |
|
Wacker Burghausen | 34 | 17 | 6 | 11 | 73:49 | 24 | 57 |
| 6 |
|
FV Illertissen | 34 | 16 | 8 | 10 | 54:40 | 14 | 56 |
| 7 |
|
TSV Aubstadt | 34 | 15 | 10 | 9 | 60:36 | 24 | 55 |
| 8 |
|
1. FC Nürnberg II | 34 | 11 | 13 | 10 | 48:48 | 0 | 46 |
| 9 |
|
VfB Eichstätt | 34 | 12 | 9 | 13 | 44:57 | -13 | 45 |
| 10 |
|
Viktoria Aschaffenburg | 34 | 12 | 8 | 14 | 46:47 | -1 | 44 |
| 11 |
|
FC Augsburg II | 34 | 12 | 8 | 14 | 57:63 | -6 | 44 |
| 12 |
|
TSV Buchbach | 34 | 10 | 11 | 13 | 40:40 | 0 | 41 |
| 13 |
|
FC Pipinsried | 34 | 11 | 6 | 17 | 45:65 | -20 | 39 |
| 14 |
|
TSV 1896 Rain | 34 | 11 | 6 | 17 | 35:63 | -28 | 39 |
| 15 |
|
SV Heimstetten | 34 | 11 | 5 | 18 | 48:62 | -14 | 38 |
| 16 |
|
FC Memmingen | 34 | 8 | 11 | 15 | 40:63 | -23 | 35 |
| 17 |
|
SC Eltersdorf | 34 | 10 | 4 | 20 | 47:74 | -27 | 34 |
| 18 |
|
SpVgg Greuther Fürth II | 34 | 7 | 10 | 17 | 39:65 | -26 | 31 |
| 19 |
|
SV Schalding-Heining | 34 | 7 | 8 | 19 | 32:65 | -33 | 29 |
| 20 |
|
TSV 1860 Rosenheim | 34 | 4 | 11 | 19 | 34:91 | -57 | 23 |
| Aufstieg | |
| Relegation | |
| Abstieg |
