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| 10.09.2021 | 19:00 | FC Nöttingen | - | Neckarsulmer Sport-Union | 2:1 (0:1) | |
| 19:30 | SSV Reutlingen | - | TSG Backnang | 0:2 (0:2) | ||
| 11.09.2021 | 14:00 | Göppinger SV | - | Freiburger FC | 2:1 (1:0) | |
| 14:00 | SGV Freiberg | - | FV Ravensburg | 4:2 (1:1) | ||
| 14:00 | FC-Astoria Walldorf II | - | FC 08 Villingen | 0:3 (0:2) | ||
| 14:00 | Sportfreunde Dorfmerkingen | - | 1. FC Bruchsal | 1:0 (0:0) | ||
| 15:30 | FSV 08 Bietigheim-Bissingen | - | TSV Ilshofen | 3:1 (2:0) | ||
| 15:30 | SV Oberachern | - | 1. FC Rielasingen-Arlen | 3:1 (3:0) | ||
| 28.09.2021 | 18:00 | FV Lörrach-Brombach | - | 1. CfR Pforzheim | 1:3 (1:3) | |
| 03.11.2021 | 19:00 | Stuttgarter Kickers | - | SV Linx | 7:0 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
TSG Backnang | 7 | 5 | 0 | 2 | 15:9 | 6 | 15 |
| 2 |
|
SGV Freiberg | 7 | 4 | 2 | 1 | 21:8 | 13 | 14 |
| 3 |
|
Stuttgarter Kickers | 7 | 4 | 2 | 1 | 15:4 | 11 | 14 |
| 4 |
|
FSV 08 Bietigheim-Bissingen | 7 | 4 | 1 | 2 | 18:9 | 9 | 13 |
|
FV Ravensburg | 7 | 4 | 1 | 2 | 18:9 | 9 | 13 | |
| 6 |
|
FC 08 Villingen | 7 | 4 | 1 | 2 | 15:9 | 6 | 13 |
| 7 |
|
Neckarsulmer Sport-Union | 7 | 4 | 1 | 2 | 15:11 | 4 | 13 |
| 8 |
|
1. FC Rielasingen-Arlen | 7 | 4 | 1 | 2 | 7:6 | 1 | 13 |
| 9 |
|
SV Linx | 7 | 4 | 1 | 2 | 10:16 | -6 | 13 |
| 10 |
|
Göppinger SV | 7 | 3 | 2 | 2 | 10:9 | 1 | 11 |
| 11 |
|
FC-Astoria Walldorf II | 7 | 3 | 1 | 3 | 10:12 | -2 | 10 |
| 12 |
|
1. CfR Pforzheim | 7 | 3 | 0 | 4 | 10:9 | 1 | 9 |
| 13 |
|
Freiburger FC | 7 | 2 | 3 | 2 | 10:10 | 0 | 9 |
| 14 |
|
SSV Reutlingen | 7 | 2 | 1 | 4 | 9:12 | -3 | 7 |
| 15 |
|
SV Oberachern | 7 | 2 | 1 | 4 | 10:17 | -7 | 7 |
| 16 |
|
FC Nöttingen | 7 | 2 | 0 | 5 | 7:15 | -8 | 6 |
| 17 |
|
Sportfreunde Dorfmerkingen | 7 | 2 | 0 | 5 | 5:19 | -14 | 6 |
| 18 |
|
1. FC Bruchsal | 7 | 1 | 2 | 4 | 8:11 | -3 | 5 |
| 19 |
|
TSV Ilshofen | 7 | 1 | 2 | 4 | 7:14 | -7 | 5 |
| 20 |
|
FV Lörrach-Brombach | 7 | 0 | 2 | 5 | 2:13 | -11 | 2 |
| Aufstieg | |
| Relegation | |
| Abstieg |
