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| 01.05.2021 | 14:00 | Ascoli Calcio | - | Empoli FC | 2:0 (1:0) | |
| 14:00 | Brescia Calcio | - | SPAL 2013 Ferrara | 3:1 (1:0) | ||
| 14:00 | Cosenza Calcio | - | Delfino Pescara | 3:0 (3:0) | ||
| 14:00 | Venezia FC | - | Chievo Verona | 3:1 (1:0) | ||
| 14:00 | Frosinone Calcio | - | AC Pisa | 3:1 (1:1) | ||
| 14:00 | AC Reggiana 1919 | - | Pordenone Calcio | 1:0 (0:0) | ||
| 14:00 | US Cremonese | - | Reggina 1914 | 1:1 (1:0) | ||
| 14:00 | US Lecce | - | AS Cittadella | 1:3 (1:1) | ||
| 14:00 | US Salernitana 1919 | - | AC Monza | 1:3 (0:0) | ||
| 14:00 | Virtus Entella | - | Vicenza Virtus | 1:2 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Empoli FC | 35 | 17 | 16 | 2 | 62:32 | 30 | 67 |
| 2 |
|
US Lecce | 35 | 16 | 13 | 6 | 65:42 | 23 | 61 |
| 3 |
|
US Salernitana 1919 | 35 | 16 | 12 | 7 | 39:33 | 6 | 60 |
| 4 |
|
AC Monza | 35 | 15 | 13 | 7 | 47:31 | 16 | 58 |
| 5 |
|
Venezia FC | 35 | 15 | 11 | 9 | 50:36 | 14 | 56 |
| 6 |
|
AS Cittadella | 35 | 14 | 11 | 10 | 46:32 | 14 | 53 |
| 7 |
|
SPAL 2013 Ferrara | 35 | 12 | 14 | 9 | 41:40 | 1 | 50 |
| 8 |
|
Chievo Verona | 35 | 12 | 13 | 10 | 43:35 | 8 | 49 |
| 9 |
|
Reggina 1914 | 35 | 12 | 12 | 11 | 38:37 | 1 | 48 |
| 10 |
|
Brescia Calcio | 35 | 12 | 11 | 12 | 52:50 | 2 | 47 |
| 11 |
|
Vicenza Virtus | 35 | 10 | 14 | 11 | 45:48 | -3 | 44 |
| 12 |
|
US Cremonese | 35 | 11 | 11 | 13 | 42:42 | 0 | 44 |
| 13 |
|
AC Pisa | 35 | 10 | 14 | 11 | 46:51 | -5 | 44 |
| 14 |
|
Frosinone Calcio | 35 | 10 | 13 | 12 | 32:41 | -9 | 43 |
| 15 |
|
Pordenone Calcio | 35 | 9 | 14 | 12 | 37:37 | 0 | 41 |
| 16 |
|
Ascoli Calcio | 35 | 10 | 10 | 15 | 33:43 | -10 | 40 |
| 17 |
|
Cosenza Calcio | 35 | 6 | 17 | 12 | 29:38 | -9 | 35 |
| 18 |
|
AC Reggiana 1919 | 35 | 9 | 7 | 19 | 29:52 | -23 | 34 |
| 19 |
|
Delfino Pescara | 35 | 6 | 11 | 18 | 28:54 | -26 | 29 |
| 20 |
|
Virtus Entella | 35 | 4 | 11 | 20 | 27:57 | -30 | 23 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
