 |
 |
|
|
| 04.12.2021 | 16:15 | Atromitos | - | Apollon Smyrnis | 4:1 (2:1) | |
| 16:15 | Volos NFC | - | Panetolikos | 1:2 (1:2) | ||
| 18:30 | OFI Heraklion | - | Olympiakos Piraeus | 1:3 (1:1) | ||
| 05.12.2021 | 16:15 | Ionikos Nikea | - | PAOK Saloniki | 3:2 (2:1) | |
| 18:30 | AEK Athen | - | Panathinaikos | 1:0 (1:0) | ||
| 18:30 | Aris Saloniki | - | Asteras Tripolis | 1:0 (1:0) | ||
| 06.12.2021 | 18:30 | Lamia | - | PAS Giannina | 0:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Olympiakos Piraeus | 12 | 10 | 2 | 0 | 23:9 | 14 | 32 |
| 2 |
|
AEK Athen | 12 | 8 | 2 | 2 | 25:14 | 11 | 26 |
| 3 |
|
Aris Saloniki | 12 | 7 | 2 | 3 | 15:11 | 4 | 23 |
| 4 |
|
PAOK Saloniki | 12 | 6 | 1 | 5 | 22:17 | 5 | 19 |
| 5 |
|
PAS Giannina | 12 | 5 | 4 | 3 | 16:8 | 8 | 19 |
| 6 |
|
OFI Heraklion | 12 | 4 | 6 | 2 | 14:12 | 2 | 18 |
| 7 |
|
Panathinaikos | 12 | 5 | 2 | 5 | 20:11 | 9 | 17 |
| 8 |
|
Volos NFC | 12 | 4 | 2 | 6 | 20:24 | -4 | 14 |
| 9 |
|
Ionikos Nikea | 12 | 3 | 4 | 5 | 11:16 | -5 | 13 |
| 10 |
|
Asteras Tripolis | 12 | 3 | 4 | 5 | 12:12 | 0 | 13 |
| 11 |
|
Panetolikos | 12 | 3 | 2 | 7 | 12:23 | -11 | 11 |
| 12 |
|
Lamia | 12 | 2 | 4 | 6 | 10:15 | -5 | 10 |
| 13 |
|
Atromitos | 12 | 2 | 3 | 7 | 13:25 | -12 | 9 |
| 14 |
|
Apollon Smyrnis | 12 | 1 | 4 | 7 | 7:23 | -16 | 7 |
| Playoffs | |
| Relegation |
