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| 22.04.2022 | 20:00 | AS Béziers | - | Andrézieux-Bouthéon FC | 3:1 (1:0) | |
| 23.04.2022 | 18:00 | Angoulême CFC | - | Canet Roussillon | 1:3 (1:1) | |
| 18:00 | Bourges Foot 18 | - | Montpellier HSC (CFA) | 2:1 (2:0) | ||
| 18:00 | Le Puy Foot 43 | - | Vendée Les Herbiers | 1:0 (1:0) | ||
| 18:00 | Angers SCO II | - | Bergerac Foot | 0:1 (0:0) | ||
| 18:00 | Trélissac FC | - | FC Nantes (CFA) | 1:0 (1:0) | ||
| 18:00 | Stade Montois | - | FC Chamalières | 2:2 (0:1) | ||
| 18:30 | Moulins Yzeure Foot | - | US Colomiers | 3:1 (1:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bergerac Foot | 26 | 15 | 8 | 3 | 31:13 | 18 | 53 |
| 2 |
|
Le Puy Foot 43 | 26 | 14 | 7 | 5 | 33:15 | 18 | 49 |
| 3 |
|
Andrézieux-Bouthéon FC | 26 | 14 | 5 | 7 | 36:23 | 13 | 47 |
| 4 |
|
Bourges Foot 18 | 26 | 13 | 5 | 8 | 36:23 | 13 | 44 |
| 5 |
|
Angoulême CFC | 26 | 12 | 8 | 6 | 30:21 | 9 | 44 |
| 6 |
|
AS Béziers | 26 | 10 | 8 | 8 | 34:28 | 6 | 38 |
| 7 |
|
Moulins Yzeure Foot | 26 | 9 | 10 | 7 | 27:25 | 2 | 37 |
| 8 |
|
Vendée Les Herbiers | 26 | 9 | 7 | 10 | 28:30 | -2 | 34 |
| 9 |
|
FC Nantes (CFA) | 26 | 8 | 9 | 9 | 28:28 | 0 | 33 |
| 10 |
|
Trélissac FC | 26 | 8 | 7 | 11 | 23:24 | -1 | 31 |
| 11 |
|
Canet Roussillon | 26 | 12 | 5 | 9 | 26:30 | -4 | 30 |
| 12 |
|
Angers SCO II | 26 | 6 | 11 | 9 | 23:26 | -3 | 29 |
| 13 |
|
FC Chamalières | 26 | 7 | 7 | 12 | 28:36 | -8 | 28 |
| 14 |
|
Montpellier HSC (CFA) | 26 | 7 | 6 | 13 | 30:38 | -8 | 27 |
| 15 |
|
US Colomiers | 26 | 5 | 9 | 12 | 26:37 | -11 | 24 |
| 16 |
|
Stade Montois | 26 | 1 | 4 | 21 | 17:59 | -42 | 7 |
| Aufstieg | |
| Abstieg |
