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| 30.04.2022 | 15:00 | AJ Auxerre | - | USL Dunkerque | 1:0 (0:0) | |
| 19:00 | AC Ajaccio | - | Havre AC | 2:1 (2:1) | ||
| 19:00 | AS Nancy Lorraine | - | Nîmes Olympique | 1:3 (0:1) | ||
| 19:00 | EA Guingamp | - | SM Caen | 2:1 (0:1) | ||
| 19:00 | Chamois Niortais | - | Dijon FCO | 1:3 (1:1) | ||
| 19:00 | Paris FC | - | Valenciennes FC | 1:1 (1:1) | ||
| 19:00 | FC Sochaux | - | SC Bastia | 2:1 (0:0) | ||
| 19:00 | Grenoble Foot 38 | - | Amiens SC | 1:1 (1:0) | ||
| 19:00 | US Quevilly-Rouen | - | Pau FC | 1:2 (1:0) | ||
| 02.05.2022 | 20:45 | Rodez AF | - | Toulouse FC | 1:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Toulouse FC | 36 | 22 | 10 | 4 | 80:31 | 49 | 76 |
| 2 |
|
AC Ajaccio | 36 | 21 | 8 | 7 | 37:18 | 19 | 71 |
| 3 |
|
AJ Auxerre | 36 | 19 | 11 | 6 | 57:37 | 20 | 68 |
| 4 |
|
FC Sochaux | 36 | 19 | 10 | 7 | 45:31 | 14 | 67 |
| 5 |
|
Paris FC | 36 | 18 | 10 | 8 | 50:34 | 16 | 64 |
| 6 |
|
EA Guingamp | 36 | 13 | 13 | 10 | 47:46 | 1 | 52 |
| 7 |
|
Havre AC | 36 | 13 | 11 | 12 | 36:37 | -1 | 50 |
| 8 |
|
Nîmes Olympique | 36 | 14 | 7 | 15 | 43:47 | -4 | 49 |
| 9 |
|
SM Caen | 36 | 12 | 11 | 13 | 49:40 | 9 | 47 |
| 10 |
|
Dijon FCO | 36 | 13 | 7 | 16 | 44:48 | -4 | 46 |
| 11 |
|
Chamois Niortais | 36 | 12 | 9 | 15 | 36:38 | -2 | 45 |
| 12 |
|
Pau FC | 36 | 13 | 6 | 17 | 36:45 | -9 | 45 |
| 13 |
|
Amiens SC | 36 | 9 | 17 | 10 | 41:37 | 4 | 44 |
| 14 |
|
SC Bastia | 36 | 9 | 16 | 11 | 36:35 | 1 | 43 |
| 15 |
|
Grenoble Foot 38 | 36 | 12 | 7 | 17 | 31:41 | -10 | 43 |
| 16 |
|
Valenciennes FC | 36 | 8 | 14 | 14 | 31:46 | -15 | 38 |
| 17 |
|
Rodez AF | 36 | 8 | 13 | 15 | 29:42 | -13 | 37 |
| 18 |
|
US Quevilly-Rouen | 36 | 9 | 10 | 17 | 30:47 | -17 | 37 |
| 19 |
|
USL Dunkerque | 36 | 8 | 7 | 21 | 26:47 | -21 | 31 |
| 20 |
|
AS Nancy Lorraine | 36 | 5 | 9 | 22 | 27:64 | -37 | 24 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
