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| 26.11.2021 | 21:00 | West Bromwich Albion | - | Nottingham Forest | 0:0 (0:0) | |
| 27.11.2021 | 13:30 | Preston North End | - | Fulham FC | 1:1 (0:1) | |
| 16:00 | AFC Bournemouth | - | Coventry City | 2:2 (1:0) | ||
| 16:00 | Birmingham City | - | Blackpool FC | 1:0 (0:0) | ||
| 16:00 | Huddersfield Town | - | Middlesbrough FC | 1:2 (0:2) | ||
| 16:00 | Hull City | - | Millwall FC | 2:1 (1:1) | ||
| 16:00 | Luton Town | - | Cardiff City | 1:2 (0:1) | ||
| 16:00 | Peterborough United | - | Barnsley FC | 0:0 (0:0) | ||
| 16:00 | Stoke City | - | Blackburn Rovers | 0:1 (0:0) | ||
| 16:00 | Swansea City | - | Reading FC | 2:3 (1:2) | ||
| 28.11.2021 | 13:30 | Sheffield United | - | Bristol City | 2:0 (1:0) | |
| 29.11.2021 | 20:45 | Derby County | - | Queens Park Rangers | 1:2 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Fulham FC | 20 | 13 | 4 | 3 | 49:16 | 33 | 43 |
| 2 |
|
AFC Bournemouth | 20 | 12 | 6 | 2 | 36:16 | 20 | 42 |
| 3 |
|
Queens Park Rangers | 20 | 10 | 5 | 5 | 33:25 | 8 | 35 |
| 4 |
|
West Bromwich Albion | 20 | 9 | 7 | 4 | 27:16 | 11 | 34 |
| 5 |
|
Blackburn Rovers | 20 | 9 | 6 | 5 | 34:27 | 7 | 33 |
| 6 |
|
Coventry City | 20 | 9 | 6 | 5 | 27:23 | 4 | 33 |
| 7 |
|
Stoke City | 20 | 9 | 4 | 7 | 24:21 | 3 | 31 |
| 8 |
|
Huddersfield Town | 20 | 8 | 4 | 8 | 23:23 | 0 | 28 |
| 9 |
|
Swansea City | 20 | 7 | 6 | 7 | 25:26 | -1 | 27 |
| 10 |
|
Millwall FC | 20 | 6 | 9 | 5 | 20:21 | -1 | 27 |
| 11 |
|
Blackpool FC | 20 | 7 | 6 | 7 | 20:22 | -2 | 27 |
| 12 |
|
Middlesbrough FC | 20 | 7 | 5 | 8 | 23:23 | 0 | 26 |
| 13 |
|
Sheffield United | 20 | 7 | 5 | 8 | 25:26 | -1 | 26 |
| 14 |
|
Birmingham City | 20 | 7 | 5 | 8 | 19:21 | -2 | 26 |
| 15 |
|
Luton Town | 20 | 6 | 7 | 7 | 27:26 | 1 | 25 |
| 16 |
|
Nottingham Forest | 20 | 6 | 7 | 7 | 24:23 | 1 | 25 |
| 17 |
|
Preston North End | 20 | 6 | 7 | 7 | 22:26 | -4 | 25 |
| 18 |
|
Bristol City | 20 | 6 | 5 | 9 | 21:30 | -9 | 23 |
| 19 |
|
Hull City | 20 | 6 | 3 | 11 | 16:23 | -7 | 21 |
| 20 |
|
Cardiff City | 20 | 6 | 3 | 11 | 21:34 | -13 | 21 |
| 21 |
|
Reading FC | 20 | 8 | 2 | 10 | 26:32 | -6 | 20 |
| 22 |
|
Peterborough United | 20 | 4 | 4 | 12 | 17:38 | -21 | 16 |
| 23 |
|
Barnsley FC | 20 | 2 | 6 | 12 | 13:31 | -18 | 12 |
| 24 |
|
Derby County | 20 | 4 | 10 | 6 | 17:20 | -3 | 1 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
|
# Derby County wurden wegen eines Insolvenzverfahrens 12 Punkte abgezogen. Neun weitere Zähler Abzug wurden wegen eines Verstoßes gegen EFL-Regeln verhängt. # Reading wurde nach einem Verstoß gegen die Gewinn- und Nachhaltigkeitsregeln der EFL mit einem Abzug von 6 Punkten bestraft. |
