 |
 |
|
|
| 26.10.2021 | 23:00 | Envigado FC | - | Millonarios | 2:1 (0:0) | |
| 27.10.2021 | 01:00 | Alianza Petrolera | - | Independiente Medellín | 3:0 (1:0) | |
| 03:05 | Deportivo Pereira | - | Atlético Bucaramanga | 1:1 (0:1) | ||
| 23:00 | La Equidad | - | Águilas Doradas | 2:2 (0:2) | ||
| 28.10.2021 | 01:00 | Deportivo Cali | - | Patriotas FC | 2:0 (0:0) | |
| 03:05 | Atlético Nacional | - | Once Caldas | 2:0 (1:0) | ||
| 21:00 | Deportivo Pasto | - | Atlético Huila | 1:0 (0:0) | ||
| 23:00 | Santa Fe | - | Jaguares de Córdoba | 3:1 (2:0) | ||
| 29.10.2021 | 01:05 | Atlético Junior | - | Deportes Quindío | 0:0 (0:0) | |
| 03:10 | Deportes Tolima | - | América de Cali | 0:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Nacional | 16 | 12 | 3 | 1 | 31:10 | 21 | 39 |
| 2 |
|
Millonarios | 16 | 10 | 2 | 4 | 30:17 | 13 | 32 |
| 3 |
|
Deportes Tolima | 16 | 7 | 7 | 2 | 17:8 | 9 | 28 |
| 4 |
|
Deportivo Pereira | 16 | 8 | 4 | 4 | 21:16 | 5 | 28 |
| 5 |
|
Envigado FC | 16 | 7 | 5 | 4 | 21:17 | 4 | 26 |
| 6 |
|
Alianza Petrolera | 16 | 7 | 4 | 5 | 23:15 | 8 | 25 |
| 7 |
|
Atlético Junior | 16 | 6 | 7 | 3 | 20:18 | 2 | 25 |
| 8 |
|
Deportivo Cali | 16 | 6 | 6 | 4 | 21:20 | 1 | 24 |
| 9 |
|
Santa Fe | 16 | 6 | 5 | 5 | 18:17 | 1 | 23 |
| 10 |
|
América de Cali | 16 | 6 | 4 | 6 | 15:15 | 0 | 22 |
| 11 |
|
Jaguares de Córdoba | 16 | 6 | 4 | 6 | 22:23 | -1 | 22 |
| 12 |
|
Atlético Bucaramanga | 16 | 6 | 4 | 6 | 23:25 | -2 | 22 |
| 13 |
|
Deportes Quindío | 16 | 6 | 3 | 7 | 16:16 | 0 | 21 |
| 14 |
|
Independiente Medellín | 16 | 4 | 8 | 4 | 12:14 | -2 | 20 |
| 15 |
|
Águilas Doradas | 16 | 5 | 2 | 9 | 19:23 | -4 | 17 |
| 16 |
|
La Equidad | 16 | 3 | 7 | 6 | 15:19 | -4 | 16 |
| 17 |
|
Deportivo Pasto | 16 | 4 | 3 | 9 | 11:20 | -9 | 15 |
| 18 |
|
Once Caldas | 16 | 3 | 3 | 10 | 13:27 | -14 | 12 |
| 19 |
|
Patriotas FC | 16 | 2 | 5 | 9 | 7:19 | -12 | 11 |
| 20 |
|
Atlético Huila | 16 | 1 | 4 | 11 | 11:27 | -16 | 7 |
| Playoffs |
