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| H | Espérance de Tunis | - | Al Ahly SC | 0:1 (0:0) | ||
| R | Al Ahly SC | - | Espérance de Tunis | 3:0 (1:0) | ||
| H: 19.06.2021 18:00 | R: 26.06.2021 21:00 | Sieger: Al Ahly SC | ||||
| H | Wydad AC | - | Kaizer Chiefs | 0:1 (0:1) | ||
| R | Kaizer Chiefs | - | Wydad AC | 0:0 (0:0) | ||
| H: 19.06.2021 21:00 | R: 26.06.2021 18:00 | Sieger: Kaizer Chiefs | ||||
