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| 29.10.2021 | 00:00 | Red Bull Bragantino | - | Sport Recife - PE | 3:0 (1:0) | |
| 20.11.2021 | 23:00 | Atlético Mineiro | - | Juventude - RS | 2:0 (0:0) | |
| 23:00 | Chapecoense | - | Grêmio Porto Alegre | 1:3 (0:1) | ||
| 23:00 | Fortaleza | - | Palmeiras | 1:0 (1:0) | ||
| 21.11.2021 | 01:00 | Atlético Goianiense | - | Ceará - CE | 1:1 (0:0) | |
| 01:30 | Internacional | - | Flamengo RJ | 1:2 (1:2) | ||
| 20:00 | Corinthians SP | - | Santos FC | 2:0 (0:0) | ||
| 21:00 | Fluminense RJ | - | América - MG | 2:0 (1:0) | ||
| 23:00 | Bahia - BA | - | Cuiabá - MT | 0:0 (0:0) | ||
| 25.11.2021 | 01:30 | São Paulo FC | - | Athletico Paranaense | 0:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Mineiro | 34 | 24 | 5 | 5 | 56:24 | 32 | 77 |
| 2 |
|
Flamengo RJ | 34 | 20 | 7 | 7 | 66:31 | 35 | 67 |
| 3 |
|
Palmeiras | 34 | 18 | 4 | 12 | 52:40 | 12 | 58 |
| 4 |
|
Corinthians SP | 34 | 14 | 11 | 9 | 37:32 | 5 | 53 |
| 5 |
|
Fortaleza | 34 | 15 | 7 | 12 | 41:41 | 0 | 52 |
| 6 |
|
Red Bull Bragantino | 34 | 13 | 13 | 8 | 50:40 | 10 | 52 |
| 7 |
|
Fluminense RJ | 34 | 13 | 9 | 12 | 33:34 | -1 | 48 |
| 8 |
|
Internacional | 34 | 12 | 11 | 11 | 42:37 | 5 | 47 |
| 9 |
|
Ceará - CE | 34 | 10 | 16 | 8 | 36:34 | 2 | 46 |
| 10 |
|
América - MG | 34 | 11 | 12 | 11 | 35:36 | -1 | 45 |
| 11 |
|
Cuiabá - MT | 34 | 9 | 16 | 9 | 31:32 | -1 | 43 |
| 12 |
|
Athletico Paranaense | 34 | 12 | 6 | 16 | 39:43 | -4 | 42 |
| 13 |
|
Santos FC | 34 | 10 | 12 | 12 | 30:38 | -8 | 42 |
| 14 |
|
São Paulo FC | 34 | 9 | 15 | 10 | 26:33 | -7 | 42 |
| 15 |
|
Atlético Goianiense | 34 | 9 | 14 | 11 | 26:34 | -8 | 41 |
| 16 |
|
Juventude - RS | 34 | 9 | 13 | 12 | 33:40 | -7 | 40 |
| 17 |
|
Bahia - BA | 34 | 9 | 10 | 15 | 35:46 | -11 | 37 |
| 18 |
|
Grêmio Porto Alegre | 34 | 10 | 6 | 18 | 35:44 | -9 | 36 |
| 19 |
|
Sport Recife - PE | 34 | 8 | 9 | 17 | 21:33 | -12 | 33 |
| 20 |
|
Chapecoense | 34 | 1 | 12 | 21 | 27:59 | -32 | 15 |
| Copa Libertadores | |
| Qualifikation | |
| Copa Sudamericana | |
| Abstieg |
