 |
 |
|
| 10.12.2021 | 20:00 | Nacional Potosí | - | Oriente Petrolero | 1:0 (0:0) | |
| 11.12.2021 | 00:00 | Bolívar | - | Royal Pari | 2:0 (1:0) | |
| 20:00 | Real Tomayapo | - | Atlético Palmaflor | 3:3 (1:1) | ||
| 20:00 | San José | - | Jorge Wilstermann | 0:3 Wert. | ||
| 12.12.2021 | 00:00 | Blooming | - | Real Potosí | 1:0 (1:0) | |
| 20:00 | CD Guabirá | - | Independiente Petrolero | 2:3 (1:1) | ||
| 20:00 | Club Aurora | - | Always Ready | 3:4 (2:0) | ||
| 20:00 | Real Santa Cruz | - | The Strongest | 1:0 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Independiente Petrolero | 30 | 20 | 5 | 5 | 59:33 | 26 | 65 |
| 2 |
|
Always Ready | 30 | 19 | 7 | 4 | 66:31 | 35 | 64 |
| 3 |
|
The Strongest | 30 | 19 | 6 | 5 | 57:24 | 33 | 63 |
| 4 |
|
Bolívar | 30 | 16 | 8 | 6 | 63:29 | 34 | 56 |
| 5 |
|
Royal Pari | 30 | 16 | 3 | 11 | 66:45 | 21 | 51 |
| 6 |
|
Oriente Petrolero | 30 | 15 | 6 | 9 | 46:29 | 17 | 51 |
| 7 |
|
Jorge Wilstermann | 30 | 15 | 4 | 11 | 64:48 | 16 | 49 |
| 8 |
|
CD Guabirá | 30 | 13 | 5 | 12 | 47:47 | 0 | 44 |
| 9 |
|
Atlético Palmaflor | 30 | 11 | 7 | 12 | 42:45 | -3 | 40 |
| 10 |
|
Nacional Potosí | 30 | 10 | 9 | 11 | 45:46 | -1 | 39 |
| 11 |
|
Real Santa Cruz | 30 | 11 | 5 | 14 | 39:47 | -8 | 38 |
| 12 |
|
Club Aurora | 30 | 9 | 6 | 15 | 40:51 | -11 | 33 |
| 13 |
|
Real Tomayapo | 30 | 9 | 5 | 16 | 28:45 | -17 | 32 |
| 14 |
|
Blooming | 30 | 7 | 5 | 18 | 34:56 | -22 | 26 |
| 15 |
|
Real Potosí | 30 | 7 | 4 | 19 | 30:63 | -33 | 25 |
| 16 |
|
San José | 30 | 0 | 1 | 29 | 9:96 | -87 | 1 |
| Copa Libertadores | |
| Copa Sudamericana | |
| Relegation | |
| Abstieg |
