 |
 |
|
|
| 14.01.2022 | 20:45 | KAA Gent | - | KV Kortrijk | 2:2 (1:1) | |
| 15.01.2022 | Oud-Heverlee Leuven | - | KV Mechelen | 5:0 Wert. | ||
| 20:45 | Club Brugge KV | - | Sint-Truidense VV | 2:0 (1:0) | ||
| 16.01.2022 | 13:30 | Royal Antwerp FC | - | Sporting Charleroi | 3:0 (2:0) | |
| 16:00 | KAS Eupen | - | Cercle Brugge | 0:2 (0:0) | ||
| 18:30 | RSC Anderlecht | - | Standard Liège | 1:1 (1:0) | ||
| 21:00 | KRC Genk | - | K Beerschot VA | 4:1 (2:0) | ||
| 18.01.2022 | 20:00 | RFC Seraing | - | Union Saint-Gilloise | 0:4 (0:2) | |
| 09.02.2022 | 18:45 | SV Zulte Waregem | - | KV Oostende | 0:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Union Saint-Gilloise | 22 | 16 | 2 | 4 | 54:20 | 34 | 50 |
| 2 |
|
Royal Antwerp FC | 22 | 13 | 4 | 5 | 42:24 | 18 | 43 |
| 3 |
|
Club Brugge KV | 22 | 12 | 7 | 3 | 43:28 | 15 | 43 |
| 4 |
|
RSC Anderlecht | 22 | 10 | 9 | 3 | 51:27 | 24 | 39 |
| 5 |
|
KAA Gent | 22 | 10 | 5 | 7 | 35:24 | 11 | 35 |
| 6 |
|
Sporting Charleroi | 22 | 10 | 5 | 7 | 38:32 | 6 | 35 |
| 7 |
|
KV Mechelen | 22 | 10 | 3 | 9 | 37:42 | -5 | 33 |
| 8 |
|
KRC Genk | 22 | 9 | 5 | 8 | 44:34 | 10 | 32 |
| 9 |
|
KV Kortrijk | 22 | 8 | 8 | 6 | 28:26 | 2 | 32 |
| 10 |
|
Oud-Heverlee Leuven | 22 | 7 | 8 | 7 | 34:34 | 0 | 29 |
| 11 |
|
Cercle Brugge | 22 | 8 | 4 | 10 | 30:28 | 2 | 28 |
| 12 |
|
Standard Liège | 22 | 7 | 6 | 9 | 24:35 | -11 | 27 |
| 13 |
|
KAS Eupen | 22 | 7 | 4 | 11 | 30:38 | -8 | 25 |
| 14 |
|
Sint-Truidense VV | 22 | 7 | 3 | 12 | 22:33 | -11 | 24 |
| 15 |
|
SV Zulte Waregem | 22 | 6 | 6 | 10 | 31:45 | -14 | 24 |
| 16 |
|
KV Oostende | 22 | 7 | 3 | 12 | 23:43 | -20 | 24 |
| 17 |
|
RFC Seraing | 22 | 6 | 1 | 15 | 23:46 | -23 | 19 |
| 18 |
|
K Beerschot VA | 22 | 2 | 3 | 17 | 16:46 | -30 | 9 |
| Playoffs | |
| Playoffs | |
| Relegation | |
| Abstieg |
