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| 14.05.2022 | 14:00 | ASV Neumarkt | - | DJK Bamberg | 1:3 (0:2) | |
| 14:00 | ATSV Erlangen | - | TSV Abtswind | 0:2 (0:1) | ||
| 14:00 | DJK Gebenbach | - | Würzburger FV | 5:3 (1:2) | ||
| 14:00 | Eintracht Bamberg | - | 1. SC Feucht | 1:3 (1:1) | ||
| 14:00 | SpVgg Ansbach | - | ASV Cham | 5:0 (2:0) | ||
| 14:00 | TSV Karlburg | - | 1. FC Sand | 2:1 (0:1) | ||
| 14:00 | Vatan Spor Aschaffenburg | - | SV Seligenporten | 2:1 (1:0) | ||
| 14:00 | DJK Vilzing | - | SpVgg Bayern Hof | 3:0 (0:0) | ||
| 15:30 | DJK Ammerthal | - | TSV Großbardorf | 3:4 (2:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
DJK Vilzing | 33 | 25 | 3 | 5 | 85:26 | 59 | 78 |
| 2 |
|
SpVgg Ansbach | 33 | 25 | 3 | 5 | 85:30 | 55 | 78 |
| 3 |
|
ATSV Erlangen | 33 | 23 | 3 | 7 | 76:35 | 41 | 72 |
| 4 |
|
Eintracht Bamberg | 33 | 21 | 5 | 7 | 81:32 | 49 | 68 |
| 5 |
|
ASV Neumarkt | 33 | 19 | 4 | 10 | 68:45 | 23 | 61 |
| 6 |
|
DJK Bamberg | 33 | 16 | 5 | 12 | 65:58 | 7 | 53 |
| 7 |
|
DJK Gebenbach | 33 | 15 | 6 | 12 | 73:62 | 11 | 51 |
| 8 |
|
TSV Abtswind | 33 | 16 | 3 | 14 | 47:51 | -4 | 51 |
| 9 |
|
1. SC Feucht | 33 | 15 | 5 | 13 | 55:42 | 13 | 50 |
| 10 |
|
DJK Ammerthal | 33 | 15 | 4 | 14 | 66:69 | -3 | 49 |
| 11 |
|
TSV Großbardorf | 33 | 13 | 5 | 15 | 55:58 | -3 | 44 |
| 12 |
|
SpVgg Bayern Hof | 33 | 11 | 6 | 16 | 55:67 | -12 | 39 |
| 13 |
|
ASV Cham | 33 | 9 | 4 | 20 | 45:75 | -30 | 31 |
| 14 |
|
Würzburger FV | 33 | 7 | 7 | 19 | 39:69 | -30 | 28 |
| 15 |
|
Vatan Spor Aschaffenburg | 33 | 7 | 7 | 19 | 34:70 | -36 | 28 |
| 16 |
|
TSV Karlburg | 33 | 5 | 12 | 16 | 22:55 | -33 | 27 |
| 17 |
|
SV Seligenporten | 33 | 6 | 3 | 24 | 40:92 | -52 | 21 |
| 18 |
|
1. FC Sand | 33 | 4 | 5 | 24 | 24:79 | -55 | 17 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
