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| 06.05.2022 | 18:30 | SV Seligenporten | - | DJK Ammerthal | 1:0 (0:0) | |
| 18:30 | TSV Großbardorf | - | ATSV Erlangen | 1:2 (1:1) | ||
| 07.05.2022 | 14:00 | Eintracht Bamberg | - | ASV Neumarkt | 2:3 (0:1) | |
| 15:00 | SpVgg Bayern Hof | - | Vatan Spor Aschaffenburg | 0:0 (0:0) | ||
| 15:00 | Würzburger FV | - | SpVgg Ansbach | 1:4 (0:3) | ||
| 16:00 | 1. FC Sand | - | DJK Vilzing | 0:7 (0:4) | ||
| 16:00 | ASV Cham | - | 1. SC Feucht | 1:3 (1:2) | ||
| 16:00 | TSV Abtswind | - | DJK Gebenbach | 1:1 (1:0) | ||
| 08.05.2022 | 15:00 | DJK Bamberg | - | TSV Karlburg | 1:1 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
DJK Vilzing | 32 | 24 | 3 | 5 | 82:26 | 56 | 75 |
| 2 |
|
SpVgg Ansbach | 32 | 24 | 3 | 5 | 80:30 | 50 | 75 |
| 3 |
|
ATSV Erlangen | 32 | 23 | 3 | 6 | 76:33 | 43 | 72 |
| 4 |
|
Eintracht Bamberg | 32 | 21 | 5 | 6 | 80:29 | 51 | 68 |
| 5 |
|
ASV Neumarkt | 32 | 19 | 4 | 9 | 67:42 | 25 | 61 |
| 6 |
|
DJK Bamberg | 32 | 15 | 5 | 12 | 62:57 | 5 | 50 |
| 7 |
|
DJK Ammerthal | 32 | 15 | 4 | 13 | 63:65 | -2 | 49 |
| 8 |
|
DJK Gebenbach | 32 | 14 | 6 | 12 | 68:59 | 9 | 48 |
| 9 |
|
TSV Abtswind | 32 | 15 | 3 | 14 | 45:51 | -6 | 48 |
| 10 |
|
1. SC Feucht | 32 | 14 | 5 | 13 | 52:41 | 11 | 47 |
| 11 |
|
TSV Großbardorf | 32 | 12 | 5 | 15 | 51:55 | -4 | 41 |
| 12 |
|
SpVgg Bayern Hof | 32 | 11 | 6 | 15 | 55:64 | -9 | 39 |
| 13 |
|
ASV Cham | 32 | 9 | 4 | 19 | 45:70 | -25 | 31 |
| 14 |
|
Würzburger FV | 32 | 7 | 7 | 18 | 36:64 | -28 | 28 |
| 15 |
|
Vatan Spor Aschaffenburg | 32 | 6 | 7 | 19 | 32:69 | -37 | 25 |
| 16 |
|
TSV Karlburg | 32 | 4 | 12 | 16 | 20:54 | -34 | 24 |
| 17 |
|
SV Seligenporten | 32 | 6 | 3 | 23 | 39:90 | -51 | 21 |
| 18 |
|
1. FC Sand | 32 | 4 | 5 | 23 | 23:77 | -54 | 17 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
