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| 29.04.2022 | 16:45 | KF Laçi | - | KF Tiranë | 1:0 (1:0) | |
| 16:45 | FK Partizani | - | Dinamo Tiranë | 3:1 (2:1) | ||
| 19:45 | KF Teuta Durrës | - | FK Kukësi | 4:1 (1:1) | ||
| 30.04.2022 | 16:45 | KS Kastrioti | - | Egnatia Rrogozhine | 2:1 (0:0) | |
| 16:45 | FK Vllaznia | - | KF Skënderbeu | 1:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KF Tiranë | 31 | 20 | 6 | 5 | 55:19 | 36 | 66 |
| 2 |
|
KF Laçi | 31 | 15 | 9 | 7 | 40:25 | 15 | 54 |
| 3 |
|
FK Partizani | 31 | 11 | 13 | 7 | 40:24 | 16 | 46 |
| 4 |
|
FK Kukësi | 31 | 12 | 10 | 9 | 42:37 | 5 | 46 |
| 5 |
|
FK Vllaznia | 31 | 10 | 15 | 6 | 38:32 | 6 | 45 |
| 6 |
|
KS Kastrioti | 31 | 13 | 4 | 14 | 28:40 | -12 | 43 |
| 7 |
|
KF Teuta Durrës | 31 | 10 | 9 | 12 | 32:41 | -9 | 39 |
| 8 |
|
Egnatia Rrogozhine | 31 | 8 | 10 | 13 | 27:39 | -12 | 34 |
| 9 |
|
Dinamo Tiranë | 31 | 5 | 8 | 18 | 16:41 | -25 | 23 |
| 10 |
|
KF Skënderbeu | 31 | 3 | 12 | 16 | 19:39 | -20 | 21 |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Relegation | |
| Abstieg |
