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| 21.08.2021 | 11:00 | SC Freiburg | - | FC Augsburg | 2:3 (0:2) | |
| 11:30 | 1. FC Heidenheim 1846 | - | VfB Stuttgart | 0:4 (0:1) | ||
| 12:00 | Kickers Offenbach | - | 1. FC Saarbrücken | 3:1 (3:0) | ||
| 12:30 | SpVgg Unterhaching | - | 1. FC Nürnberg | 1:2 (0:1) | ||
| 13:00 | Stuttgarter Kickers | - | 1899 Hoffenheim | 3:5 (2:2) | ||
| 13:00 | SSV Ulm 1846 | - | Bayern München | 1:0 (1:0) | ||
| 15:00 | SV Darmstadt 98 | - | Eintracht Frankfurt | 2:1 (1:1) | ||
| 22.08.2021 | 11:00 | 1. FC Kaiserslautern | - | Hessen Kassel | 1:3 (0:0) | |
| 12:00 | FC-Astoria Walldorf | - | 1. FSV Mainz 05 | 1:7 (0:5) | ||
| 25.08.2021 | 18:30 | FC Ingolstadt 04 | - | SpVgg Greuther Fürth | 2:1 (1:0) |
| » Tabelle | Heim | Auswärts | Hinrunde | Rückrunde | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VfB Stuttgart | 2 | 2 | 0 | 0 | 7:0 | 7 | 6 |
| 2 |
|
1899 Hoffenheim | 2 | 2 | 0 | 0 | 11:5 | 6 | 6 |
| 3 |
|
FC Augsburg | 2 | 2 | 0 | 0 | 6:3 | 3 | 6 |
| 4 |
|
1. FC Nürnberg | 2 | 2 | 0 | 0 | 5:3 | 2 | 6 |
| 5 |
|
Eintracht Frankfurt | 2 | 1 | 0 | 1 | 9:4 | 5 | 3 |
| 6 |
|
1. FSV Mainz 05 | 2 | 1 | 0 | 1 | 8:4 | 4 | 3 |
| 7 |
|
Bayern München | 2 | 1 | 0 | 1 | 4:2 | 2 | 3 |
| 8 |
|
Karlsruher SC | 1 | 1 | 0 | 0 | 3:1 | 2 | 3 |
| 9 |
|
SpVgg Unterhaching | 2 | 1 | 0 | 1 | 3:2 | 1 | 3 |
| 10 |
|
SSV Ulm 1846 | 1 | 1 | 0 | 0 | 1:0 | 1 | 3 |
| 11 |
|
FC Ingolstadt 04 | 2 | 1 | 0 | 1 | 4:4 | 0 | 3 |
|
Kickers Offenbach | 2 | 1 | 0 | 1 | 4:4 | 0 | 3 | |
| 13 |
|
Hessen Kassel | 2 | 1 | 0 | 1 | 3:3 | 0 | 3 |
| 14 |
|
SV Darmstadt 98 | 2 | 1 | 0 | 1 | 2:4 | -2 | 3 |
| 15 |
|
1. FC Heidenheim 1846 | 2 | 1 | 0 | 1 | 2:5 | -3 | 3 |
| 16 |
|
SpVgg Greuther Fürth | 2 | 0 | 1 | 1 | 2:3 | -1 | 1 |
| 17 |
|
FC-Astoria Walldorf | 2 | 0 | 1 | 1 | 2:8 | -6 | 1 |
| 18 |
|
1. FC Saarbrücken | 2 | 0 | 0 | 2 | 2:5 | -3 | 0 |
| 19 |
|
SC Freiburg | 2 | 0 | 0 | 2 | 3:7 | -4 | 0 |
| 20 |
|
1. FC Kaiserslautern | 2 | 0 | 0 | 2 | 3:9 | -6 | 0 |
| 21 |
|
Stuttgarter Kickers | 2 | 0 | 0 | 2 | 5:13 | -8 | 0 |
| Playoffs | |
| Abstieg |
