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| 23.05.1981 | 17:30 | FC Nordstern Basel | - | FC Chiasso | 1:0 (1:0) | |
| 18:00 | BSC Young Boys | - | FC Zürich | 0:0 (0:0) | ||
| 20:00 | Grasshopper Club Zürich | - | CS Chênois | 2:1 (0:0) | ||
| 20:00 | AC Bellinzona | - | FC Basel | 1:1 (0:0) | ||
| 20:00 | FC Luzern | - | FC Sion | 2:2 (1:2) | ||
| 20:00 | Servette FC | - | Neuchâtel Xamax FC | 0:2 (0:1) | ||
| 20:30 | Lausanne Sports | - | FC St. Gallen | 0:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Zürich | 24 | 17 | 3 | 4 | 50:27 | 23 | 37:11 |
| 2 |
|
Grasshopper Club Zürich | 24 | 11 | 11 | 2 | 43:21 | 22 | 33:15 |
| 3 |
|
Neuchâtel Xamax FC | 24 | 13 | 6 | 5 | 41:24 | 17 | 32:16 |
| 4 |
|
BSC Young Boys | 24 | 10 | 10 | 4 | 41:31 | 10 | 30:18 |
| 5 |
|
Lausanne Sports | 24 | 11 | 5 | 8 | 36:27 | 9 | 27:21 |
| 6 |
|
FC Basel | 24 | 9 | 8 | 7 | 45:41 | 4 | 26:22 |
| 7 |
|
Servette FC | 24 | 7 | 9 | 8 | 35:34 | 1 | 23:25 |
| 8 |
|
FC Sion | 24 | 7 | 8 | 9 | 32:37 | -5 | 22:26 |
| 9 |
|
FC Luzern | 24 | 6 | 9 | 9 | 38:42 | -4 | 21:27 |
| 10 |
|
FC St. Gallen | 24 | 7 | 7 | 10 | 33:38 | -5 | 21:27 |
| 11 |
|
FC Chiasso | 24 | 5 | 8 | 11 | 28:41 | -13 | 18:30 |
| 12 |
|
AC Bellinzona | 24 | 6 | 5 | 13 | 23:43 | -20 | 17:31 |
| 13 |
|
FC Nordstern Basel | 24 | 5 | 6 | 13 | 23:36 | -13 | 16:32 |
| 14 |
|
CS Chênois | 24 | 2 | 9 | 13 | 21:47 | -26 | 13:35 |
| Champions League | |
| Europa League | |
| Abstieg |
