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| H | Royal Pari | - | La Equidad | 1:2 (1:0) | ||
| R | La Equidad | - | Royal Pari | 2:1 (0:1) | ||
| H: 10.07.2019 02:30 | R: 17.07.2019 02:30 | Sieger: La Equidad | ||||
| H | Caracas FC | - | Independiente del Valle | 0:0 (0:0) | ||
| R | Independiente del Valle | - | Caracas FC | 2:0 (0:0) | ||
| H: 10.07.2019 22:00 | R: 18.07.2019 02:30 | Sieger: Independiente del Valle | ||||
| H | Colón de Santa Fe | - | Argentinos Juniors | 0:1 (0:1) | ||
| R | Argentinos Juniors | - | Colón de Santa Fe | 3:4 (0:0, 0:1) i.E. | ||
| H: 12.07.2019 02:30 | R: 19.07.2019 02:30 | Sieger: Colón de Santa Fe | ||||
| H | Zulia FC | - | Sporting Cristal | 1:0 (0:0) | ||
| R | Sporting Cristal | - | Zulia FC | 3:2 (0:1) | ||
| H: 23.07.2019 22:00 | R: 31.07.2019 00:15 | Sieger: Zulia FC | ||||
| H | Peñarol | - | Fluminense RJ | 1:2 (0:1) | ||
| R | Fluminense RJ | - | Peñarol | 3:1 (2:0) | ||
| H: 24.07.2019 02:30 | R: 31.07.2019 02:30 | Sieger: Fluminense RJ | ||||
| H | Botafogo - RJ | - | Atlético Mineiro | 0:1 (0:1) | ||
| R | Atlético Mineiro | - | Botafogo - RJ | 2:0 (0:0) | ||
| H: 25.07.2019 02:30 | R: 01.08.2019 02:30 | Sieger: Atlético Mineiro | ||||
| H | Corinthians SP | - | Montevideo Wanderers | 2:0 (1:0) | ||
| R | Montevideo Wanderers | - | Corinthians SP | 1:2 (0:0) | ||
| H: 26.07.2019 02:30 | R: 02.08.2019 02:30 | Sieger: Corinthians SP | ||||
| H | Independiente | - | Universidad Catolica | 1:0 (0:0) | ||
| R | Universidad Catolica | - | Independiente | 3:2 (1:0) | ||
| H: 26.07.2019 02:30 | R: 02.08.2019 02:30 | Sieger: Independiente | ||||
