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| 22.02.2019 | 23:00 | Tigre | - | Patronato de Paraná | 2:1 (1:1) | |
| 23.02.2019 | 01:10 | Colón de Santa Fe | - | Banfield | 0:1 (0:1) | |
| 01:10 | Lanús | - | Rosario Central | 2:0 (1:0) | ||
| 21:10 | Huracán | - | Unión de Santa Fe | 1:3 (0:2) | ||
| 21:10 | Godoy Cruz | - | Vélez Sarsfield | 0:2 (0:1) | ||
| 23:20 | Belgrano de Córdoba | - | San Lorenzo | 0:0 (0:0) | ||
| 24.02.2019 | 01:30 | Independiente | - | Racing Club | 1:3 (1:1) | |
| 21:10 | River Plate | - | San Martín de Tucumán | 2:1 (1:0) | ||
| 23:20 | Estudiantes | - | Talleres de Córdoba | 0:1 (0:0) | ||
| 23:20 | Atlético Tucumán | - | Argentinos Juniors | 0:0 (0:0) | ||
| 25.02.2019 | 01:30 | Defensa y Justicia | - | Boca Juniors | 0:1 (0:0) | |
| 23:00 | Aldosivi | - | Gimnasia de La Plata | 0:0 (0:0) | ||
| 26.02.2019 | 01:10 | Newell's Old Boys | - | San Martín de San Juan | 3:0 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Racing Club | 20 | 15 | 3 | 2 | 38:13 | 25 | 48 |
| 2 |
|
Defensa y Justicia | 20 | 13 | 6 | 1 | 27:12 | 15 | 45 |
| 3 |
|
Boca Juniors | 20 | 11 | 5 | 4 | 29:15 | 14 | 38 |
| 4 |
|
Atlético Tucumán | 20 | 10 | 6 | 4 | 33:23 | 10 | 36 |
| 5 |
|
River Plate | 20 | 9 | 6 | 5 | 30:16 | 14 | 33 |
| 6 |
|
Vélez Sarsfield | 20 | 9 | 6 | 5 | 26:21 | 5 | 33 |
| 7 |
|
Huracán | 20 | 8 | 8 | 4 | 24:20 | 4 | 32 |
| 8 |
|
Unión de Santa Fe | 20 | 8 | 6 | 6 | 22:18 | 4 | 30 |
| 9 |
|
Independiente | 20 | 7 | 8 | 5 | 29:22 | 7 | 29 |
| 10 |
|
Aldosivi | 20 | 8 | 5 | 7 | 17:19 | -2 | 29 |
| 11 |
|
Talleres de Córdoba | 20 | 7 | 6 | 7 | 19:16 | 3 | 27 |
| 12 |
|
Banfield | 20 | 6 | 9 | 5 | 21:21 | 0 | 27 |
| 13 |
|
Lanús | 20 | 7 | 6 | 7 | 21:22 | -1 | 27 |
| 14 |
|
Godoy Cruz | 20 | 8 | 2 | 10 | 19:26 | -7 | 26 |
| 15 |
|
Newell's Old Boys | 20 | 6 | 7 | 7 | 19:14 | 5 | 25 |
| 16 |
|
Tigre | 20 | 6 | 7 | 7 | 28:35 | -7 | 25 |
| 17 |
|
Estudiantes | 20 | 5 | 6 | 9 | 18:23 | -5 | 21 |
| 18 |
|
Colón de Santa Fe | 20 | 4 | 9 | 7 | 18:24 | -6 | 21 |
| 19 |
|
Rosario Central | 20 | 5 | 6 | 9 | 13:23 | -10 | 21 |
| 20 |
|
San Martín de San Juan | 20 | 5 | 4 | 11 | 19:29 | -10 | 19 |
| 21 |
|
Gimnasia de La Plata | 20 | 5 | 4 | 11 | 15:28 | -13 | 19 |
| 22 |
|
San Lorenzo | 20 | 2 | 12 | 6 | 17:23 | -6 | 18 |
| 23 |
|
San Martín de Tucumán | 20 | 3 | 9 | 8 | 19:30 | -11 | 18 |
| 24 |
|
Patronato de Paraná | 20 | 4 | 5 | 11 | 23:31 | -8 | 17 |
| 25 |
|
Belgrano de Córdoba | 20 | 2 | 11 | 7 | 11:19 | -8 | 17 |
| 26 |
|
Argentinos Juniors | 20 | 3 | 6 | 11 | 8:20 | -12 | 15 |
| Copa Libertadores | |
| Copa Sudamericana | |
| Copa Sudamericana |
|
# Der Verein Tigre ist nach dem Abstieg in die zweite Liga für internationale Spiele ausgeschlossen worden. Für den Klub rückt Huracán in die Copa Sudamericana nach. |
